We compare genetic profiles of the metastatic pancreatic cancer cell line SW1990 with two control cell lines.
We identify genes and pathways in SW1990 cells that are induced by treatment with REG3A or IL6.
We confirm eight genes and four pathways of REG3A on tumorigenesis in SW1990.
REG3A shares similar molecular mechanism with IL6.
Regulation network analysis uncovers three transcription factor families with immune functions regulated by REG3A.