The role of the mean platelet volume and neutrophil-to-lymphocyte ratio in peritonsillar abscesses

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• 作者：Mehmet Şentü ; rk ; ^{drmehmetsenturk@gmail.com" class="auth_mail" title="E-mail the corresponding author} ; İsa Azgın ; Gü ; ltekin Ö ; vet ; Necat Alataş ; Betü ; l Ağırgö ; l ; Esra Yılmaz
• 关键词：Mean platelet volume ; Neutrophil-to-lymphcyte rate ; Peritonsillar abscess ; Treatment
• 刊名：Brazilian Journal of Otorhinolaryngology
• 出版年：2016
• 出版时间：November-December 2016
• 年：2016
• 卷：82
• 期：6
• 页码：662-667
• 全文大小：526 K

文摘

Peritonsillar abscess is a serious infectious disease of the tonsillar tissue. Treatment generally requires both medical and surgical approaches to relieve the symptoms. Recently, in addition to clinical follow-up, some inflammatory markers, such as the mean platelet volume and neutrophil-to-lymphocyte ratio, have been considered to be additional inflammatory monitoring markers in inflammatory diseases.

Objective

The aim of this study was to describe the role of mean platelet volume and neutrophil-to-lymphocyte ratio in patients with peritonsillar abscess.

Methods

A retrospective study was conducted in 88 patients with peritonsillar abscess and 88 healthy individuals. We analyzed the white blood cell count, neutrophil count, lymphocyte count, platelet count, C-reactive protein, mean platelet volume and neutrophil-to-lymphocyte ratio values and compared them among the patient and control groups.

Results

The mean platelet volume levels were significantly higher in the peritonsillar abscess pretreatment group than in the peritonsillar abscess posttreatment group and the control group. A mean platelet volume value of 8.7 was the optimal cut-off value for evaluating the sensitivity, specificity, positive predictive value and negative predictive value of 75%, 65.9%, 68% and 72%, respectively. The neutrophil-to-lymphocyte ratio levels were significantly higher in the peritonsillar abscess pretreatment group than in the peritonsillar abscess post-treatment group and the control group. A neutrophil-to-lymphocyte ratio value of 3.08 was the optimal cut-off value for evaluating the sensitivity, specificity, positive predictive value and negative predictive value of 90.9%, 90.9%, 90.9% and 90.9%, respectively. While the white blood cell count, neutrophil count, lymphocyte count and C-reactive protein values were significantly different among the patient and control groups (p < 0.05), the platelet count was not significantly different among the patient and control groups (p > 0.05).

Conclusion

The mean platelet volume and neutrophil-to-lymphocyte ratio values made us think that these parameters were quick, inexpensive and reliable inflammatory follow-up parameters and could be easily integrated into daily practice for peritonsillar abscess treatment except platelet count.