刊名:Journal of Pharmaceutical and Biomedical Analysis
出版年:2017
出版时间:20 March 2017
年:2017
卷:136
期:Complete
页码:44-54
全文大小:2515 K
卷排序:136
文摘
The liver damage of GA (15:1) was studied by NMR-based metabolomics approach for the first time. The serum biochemical parameters were altered by GA (15:1) treatment in a dose-dependent manner. SUS plot showed common features of GA (15:1) dosing and dose-dependent metabolic changes. GA (15:1) induced disturbance in purine metabolism contributed to its antitumor and toxic effects.