Human uterine fibroblasts are susceptible to Zika virus infection.
Both African and Puerto Rican Zika strains can infect human uterine fibroblasts.
A quantitative reverse transcription PCR with primers targeting the envelop regions of the virus was utilized.
Uterine fibroblasts continually produced virus, while maintaining cellular viability over 5 days.
Uterine fibroblasts may be linked with heterosexual transmission of Zika virus in women.