- 作者：Yoshiyuki Takami ; Kazuyoshi Tajima ; Wataru Kato ; Kei Fujii ; Makoto Hibino ; Hisaaki Munakata ; Yoshimasa Sakai
- 关键词：CK ; creatine kinase ; CK-MB ; creatine kinase myocardial band ; ITA ; internal thoracic artery ; LAD ; left anterior descending ; OPCAB ; off-pump coronary artery bypass ; RCA ; right coronary artery ; TVI ; time-velocity integral
- 刊名：The Journal of Thoracic and Cardiovascular Surgery
- 出版年：January, 2014
- 年：2014
- 卷：147
- 期：1
- 页码：259-263
- 全文大小：486 K
Objectives
Intracoronary shunts have been developed for a bloodless field and preserved forward flow preventing ischemia during off-pump coronary artery bypass (OPCAB) surgery. However, reports directly measuring the forward flow through the shunt in clinical settings are lacking.Methods
Using a 7.5-MHz Doppler probe, we investigated the coronary flow through a 1.5-mm shunt inserted into the left anterior descending artery (LAD) for anastomosis with the internal thoracic artery during OPCAB in 30 consecutive patients. The following Doppler flow parameters were obtained before and after shunting: peak velocity, mean velocity, time-velocity integral, and flow.
Results
No patients developed significant electrocardiographic changes and the peak value of postoperative myocardial band of creatine kinase was 17 卤 16 IU/L. All Doppler flow parameters of the LAD decreased significantly after shunting; peal velocity: 71.3 卤 34.6 cm/second to 54.5 卤 25.3 cm/second (鈭?4% 卤 27%), mean velocity: 33.3 卤 18.3 cm/second to 26.3 卤 14.0 cm/second (鈭?1% 卤 23%), and time-velocity integral: 28.7 卤 12.1 cm to 19.0 卤 7.1 cm (鈭?8% 卤 14%), and flow: 38.7 卤 16.8 mL/minute to 25.0 卤 9.5 mL/minute (鈭?1% 卤 13%) (P聽<聽.01).
Conclusions
The LAD flow is preserved at least 50% through a 1.5-mm intracoronary shunt, although the flow pattern was attenuated, during OPCAB anastomosis. The Doppler evaluation of the coronary artery flow before and after shunting is useful to justify the protective use of the shunt on myocardial perfusion during OPCAB.