Degradable UV-crosslinked hydrogel for the controlled release of triclosan with reduced cytotoxicity
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- 作者：Yunfeng Hua ; Guangli Renb ; Liehua Denga ; liehuadeng@126.com" class="auth_mail" title="E-mail the corresponding author ; Jinglin Zhangc ; Huidi Liud ; Shansong Mue ; Ting Wuc ; angelwu2006@163.com" class="auth_mail" title="E-mail the corresponding author
- 关键词：Triclosan ; UV-crosslinked hydrogel ; Degradable ; Controlled release ; Bioactivity ; Cytotoxicity
- 刊名：Materials Science & Engineering C
- 出版年：2016
- 出版时间：1 October 2016
- 年：2016
- 卷：67
- 期：Complete
- 页码：151-158
- 全文大小：1637 K
文摘
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Triclosan (TC) was loaded into a degradable UV-crosslinked hydrogel.
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TC loaded hydrogel sustainably released TC with reduced side effects.
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TC-loaded hydrogel showed slight cytotoxicity.
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TC-loaded hydrogel displayed excellent biocompatibility in vitro and in vivo.