The effect of porosity and stiffness of glutaraldehyde cross-linked egg white scaffold simulating aged extracellular matrix on distribution and aggregation of ovarian cancer cells
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- 作者：Zhenchao Guoa ; b ; c ; Tianzhu Zhanga ; b ; zhangtianzhu@seu.edu.cn" class="auth_mail" title="E-mail the corresponding author ; zhangtianzhuglq@sina.com" class="auth_mail" title="E-mail the corresponding author ; Kun Fanga ; b ; Peidang Liud ; Miao Lid ; Ning Gua ; b
- 关键词：Porosity ; Stiffness ; Glutaraldehyde crosslinked egg white ; Distribution ; Aggregation ; Ovarian cancer cells
- 刊名：Colloids and Surfaces A: Physicochemical and Engineering Aspects
- 出版年：2016
- 出版时间：5 September 2016
- 年：2016
- 卷：504
- 期：Complete
- 页码：43-52
- 全文大小：4993 K
文摘
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Ovarian SKOV-3 cancer cells could form into multicellular aggregates (MCS) in GA cross-linked egg white (EW) with higher elastic modulus.
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The higher elastic modulus G′ of EW is more beneficial to the proliferation and migration of SKOV-3 cells.
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The degradable GA cross-linked EW is potential 3D cell culture matrix economically.