Rapid analysis of drug dissolution by paper spray ionization mass spectrometry

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• 作者：Yang Liu ; ^{yangliu@nifdc.org.cn} ; Ning Liu ; Ya-nan Zhou ; Lan Lin ; Lan He ; ^{helan1961@aliyun.com}
• 关键词：Paper spray ionization ; Mass spectrometry ; Dissolution test
• 刊名：Journal of Pharmaceutical and Biomedical Analysis
• 出版年：2017
• 出版时间：20 March 2017
• 年：2017
• 卷：136
• 期：Complete
• 页码：106-110
• 全文大小：855 K
• 卷排序：136

文摘

A paper based ionization method to measure the content of drugs in dissolution media is proposed. The method is compatible with phosphate potassium and acetate sodium buffer which are widely used in dissolution tests. New method is simple, rapid and precise.