Antivirals: Past, present and future

详细信息    查看全文

• 作者：Erik De Clercq ; ^{erik.declercq@rega.kuleuven.be}
• 关键词：Antivirals ; Past ; Present ; Future ; HIV ; HCV ; HBV ; HSV ; VZV ; CMV ; HFV
• 刊名：Biochemical Pharmacology
• 出版年：2013
• 出版时间：15 March, 2013
• 年：2013
• 卷：85
• 期：6
• 页码：727-744
• 全文大小：3279 K

文摘

Vaccination is possible to prevent infections with some viruses: hepatitis B virus (HBV), varicella-zoster virus (VZV), influenza A and B viruses, Yellow fever virus and poliovirus; but not for others: human immunodeficiency virus (HIV), hepatitis C virus (HCV), herpes simplex virus (HSV), cytomegalovirus (CMV), and most hemorrhagic fever viruses (HFV) (except for Yellow fever virus). Antiviral therapy is obviously needed to control those infections that are not amenable to prophylaxis by vaccination, but is also highly desirable for those infections where vaccination has not been implemented or did not fulfill its premises for complete protection.