The role of autophagy in the pathogenesis of systemic lupus erythematosus
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- 作者：Xiao Liu liuxiao19922010@163.com" class="auth_mail" title="E-mail the corresponding author ; Haihong Qin tjqhh1982@163.com" class="auth_mail" title="E-mail the corresponding author ; Jinhua Xu ; xjhhs2011@163.com" class="auth_mail" title="E-mail the corresponding author
- 关键词：Systemic lupus erythematosus ; Autophagy ; Genes ; Immunity ; Therapy
- 刊名：International Immunopharmacology
- 出版年：2016
- 出版时间：November 2016
- 年：2016
- 卷：40
- 期：Complete
- 页码：351-361
- 全文大小：1292 K
文摘
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Autophagy participates in almost every step of immune responses.
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Autophagy is aberrant in lupus immune cells, such as T cells and B cells.
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Drugs, associated with SLE treatment, can influence autophagy via different ways.
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GWAS revealed SNPs in some autophagy-related genes related to SLE susceptibility.