TAFI deficiency in liver cirrhosis: Relation with plasma fibrinolysis and survival
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- 作者：Paolo Gresele ; Bianca M. Binetti ; Giovanna Branca ; Carlo Clerici ; Stefania Asciutti ; Antonio Morelli ; Nicola Semeraro ; Mario Colucci
- 关键词：Child– ; Pugh class ; Fibrinolysis ; Inflammation ; Survival
- 刊名：Thrombosis Research
- 出版年：2008
- 出版时间：2008
- 年：2008
- 卷：121
- 期：6
- 页码：763-768
- 全文大小：173 K
文摘
TAFI (thrombin-activatable fibrinolysis inhibitor) is a potent anti-fibrinolytic and anti-inflammatory factor of liver origin. It is markedly reduced in liver cirrhosis but its effect on fibrinolysis remains controversial and no data are available on its prognostic value. We evaluated the relationship of TAFI level with plasma fibrinolysis and survival in cirrhotic patients.