A tonsillectomy increased the risk of chronic rhinosinusitis among children: A three-year follow-up study

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• 作者：Shiu-Dong Chung^a ; ^b ; ^c ; ¹ ; Herng-Ching Lin^c ; ¹ ; Chuan-Song Wu^d ; Li-Ting Kao^e ; Shih-Han Hung^f ; ^g ; ^{seedturtle@gmail.com" class="auth_mail" title="E-mail the corresponding author}
• 关键词：Tonsillectomy ; Chronic rhinosinusitis ; Epidemiology
• 刊名：International Journal of Pediatric Otorhinolaryngology
• 出版年：2016
• 出版时间：December 2016
• 年：2016
• 卷：91
• 期：Complete
• 页码：82-85
• 全文大小：197 K

文摘

The study aimed to estimate the risk of developing chronic rhinosinusitis (CRS) among children who had undergone a tonsillectomy by utilizing a cohort study based on a population-based database.

Methods

Data for this retrospective cohort study were sourced from the Taiwan ”Longitudinal Health Insurance Database 2000”. We included 202 children who had undergone a tonsillectomy as the study group and 2020 sex- and age-matched children as the comparison group. We used stratified Cox proportional hazard regressions to calculate the hazard ratio (HR) and its corresponding 95% confidence interval (CI) for CRS during the 3-year follow-up period.

Results

Of 2222 sampled children, the incidence rate of CRS during the 3-year follow-up period was 3.2 (95% CI = 2.0–4.8) 1000 person-years; 18.2 (95% CI = 9.1–32.5) per 1000 person-years and 1.7 (95% CI = 0.8–3.0) per 1000 person-years for the study and comparison group, respectively. The stratified Cox proportional analysis showed that the adjusted hazard ratio for CRS during the 3-year follow-up period was 8.28 (95% CI = 3.24–21.16) for children who had undergone a tonsillectomy than comparison patients.

Conclusions

We demonstrated that the risk of developing CRS is significantly increased among children who have undergone a tonsillectomy.