Hippocampal cytosolic estrogen receptors regulate fear generalization in females
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- 作者：Joseph F. Lynch III ; Patrick Winiecki ; Tyler Vanderhoof ; David C. Riccio ; Aaron M. Jasnow ; ajasnow@kent.edu" class="auth_mail" title="E-mail the corresponding author
- 关键词：Contextual memory precision ; Fear generalization ; Estradiol ; Hippocampus ; Contextual fear ; Memory retrieval
- 刊名：Neurobiology of Learning and Memory
- 出版年：2016
- 出版时间：April 2016
- 年：2016
- 卷：130
- 期：Complete
- 页码：83-92
- 全文大小：974 K
文摘
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Estradiol induces fear generalization to neutral contexts.
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This effect is due in part, to activation of ER and modulation of memory retrieval.
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E2-induced fear generalization is mediated through cytosolic ER in the hippocampus.