- 作者：Qing-Hua Tian ; MD ; Xi-Qi Sun ; MD ; Ying-Ying Lu ; MD ; Tao Wang ; MD ; Chun-Gen Wu ; MD ; PhD ; 649514608@qq.com" class="auth_mail" title="E-mail the corresponding author ; Ming-Hua Li ; MD ; PhD ; Ying-Sheng Cheng ; MD ; PhD
- 关键词：KPS ; Karnofsky Performance Scale ; ODI ; Oswestry Disability Index ; PMMA ; polymethyl methacrylate ; PVP ; percutaneous vertebroplasty ; VAS ; visual analog scale
- 刊名：Journal of Vascular and Interventional Radiology
- 出版年：2016
- 出版时间：September 2016
- 年：2016
- 卷：27
- 期：9
- 页码：1420-1424
- 全文大小：320 K
Materials and Methods
PVP was performed in 39 consecutive patients (median age, 60.1 y ± 9.5) with 51 osteoblastic metastatic spinal lesions; 14 patients had pathologic fractures. The patients were followed for 3–30 months (average, 14.5 mo ± 7.4). Visual analog scale (VAS), Oswestry Disability Index (ODI), and Karnofsky performance scale (KPS) were used to evaluate pain, quality of life, and performance status before the procedure and at 3 days and 1, 3, 6, 12, and 18 months after the procedure.
Results
Technical success was achieved in all patients. Minimal follow-up time was 3 months. Mean VAS scores declined significantly from 7.4 ± 1.1 before the procedure to 2.5 ± 0.9 by day 3 after the procedure and were 2.1 ± 1.1 at 1 month, 2.0 ± 1.1 at 3 months, 1.9 ± 1.1 at 6 months, 1.8 ± 0.9 at 12 months, and 1.7 ± 0.7 at 18 months after the procedure (P < .001). ODI and KPS scores also changed after the procedure, with significant differences between baseline scores and at each follow-up examination (P < .001). Extraosseous cement leakage occurred in 15 cases without causing any clinical complications.
Conclusions
PVP is a safe and effective treatment for painful osteoblastic spinal metastases. It can relieve pain, reduce disability, and improve function.