Nonductal Pancreatic Cancers

详细信息    查看全文

• 作者：Sun-Young Jun ; MD ; PhD^a ; Seung-Mo Hong ; MD ; PhD^b ; ^{smhong28@gmail.com" class="auth_mail" title="E-mail the corresponding author}
• 关键词：Pancreas ; Solid pseudopapillary ; Acinar ; Pancreatoblastoma
• 刊名：Surgical Pathology Clinics
• 出版年：2016
• 出版时间：December 2016
• 年：2016
• 卷：9
• 期：4
• 页码：581-593
• 全文大小：9221 K

文摘

Nonductal pancreatic neoplasms, including solid pseudopapillary neoplasms, acinar cell carcinomas, and pancreatoblastomas, are uncommon. These entities share overlapping gross, microscopic, and immunohistochemical features, such as well-demarcated solid neoplasms, monotonous cellular tumor cells with little intervening stroma, and abnormal beta-catenin expression. Each tumor also has unique clinicopathologic characteristics with diverse clinical behavior. To differentiate nonductal pancreatic neoplasms, identification of histologic findings, such as pseudopapillae, acinar cell features, and squamoid corpuscles, is important. Immunostainings for acinar cell or neuroendocrine markers are helpful for differential diagnosis. This article describes the clinicopathologic and immunohistochemical features of nonductal pancreatic cancers.