Comparison of clinical outcomes between ABO-compatible and ABO-incompatible spousal donor kidney transplantation

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• 作者：Woo Yeong Park¹ ; ³ ; Seong Sik Kang¹ ; ³ ; Sung Bae Park¹ ; ³ ; Ui Jun Park² ; ³ ; Hyong Tae Kim² ; ³ ; Won Hyun Cho² ; ³ ; Seungyeup Han¹ ; ³ ; ^{hansy@dsmc.or.kr" class="auth_mail" title="E-mail the corresponding author}
• 关键词：Blood group incompatibility ; Kidney transplantation ; Spouses
• 刊名：Kidney Research and Clinical Practice
• 出版年：2016
• 出版时间：March 2016
• 年：2016
• 卷：35
• 期：1
• 页码：50-54
• 全文大小：471 K

文摘

Kidney transplantation (KT) is the treatment of choice for end-stage renal disease patients. The spouse is a major donor in living KT. Clinical outcomes of spousal donor KT are not inferior to those of living related donor KT. In this study, we compared clinical outcomes between ABO-compatible (ABOc) and ABO-incompatible (ABOi) spousal donor KTs.

Methods

Thirty-two cases of spousal donor KT performed from January 2011 to August 2013 were analyzed retrospectively. Twenty-one ABOc KTs and 11 ABOi KTs were performed. We investigated patient survival, graft survival, acute rejection, graft function, and complications.

Results

During follow-up, patient and graft survival rates were 100% in both groups. There were no significant differences in the incidence of delayed graft function, acute rejection, and the change in graft function between the 2 groups. Medical and surgical complications were not significantly different between the groups.

Conclusion

The clinical outcomes of ABOc and ABOi spousal donor KTs were equivalent. In ABOi KT, an emotionally motivated spousal donor KT may be a good alternative to the problem of the absolute shortage of kidney donations.