Distinctive downmodulation of plasmacytoid dendritic cell functions by vitamin D3 analogue calcipotriol
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- 作者：Takahiro Suzuki ; tachan_suzuki@yahoo.co.jp" class="auth_mail" title="E-mail the corresponding author ; Kazuki Tatsuno ; Taisuke Ito ; Jun-ichi Sakabe ; Atsuko Funakoshi ; Yoshiki Tokura
- 刊名：Journal of Dermatological Science
- 出版年：2016
- 出版时间：October 2016
- 年：2016
- 卷：84
- 期：1
- 页码：71-79
- 全文大小：728 K
文摘
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Calcipotriol (CAL) exerts immunomodulating effects on murine plasmacytoid dendritic cells (pDCs).
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CAL inhibited IFN-α production from pDCs.
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CAL depressed chemotactic activities of pDCs toward chemokines.
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CAL may improve psoriasis by inhibiting pDCs.