Copper-Mediated Synthesis of Tertiary Diaryl Squaramides

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• 作者：Vijayakumar Ramalingam ; Niala Bhagirath ; Rajeev S. Muthyala
• 刊名：Journal of Organic Chemistry
• 出版年：2007
• 出版时间：May 11, 2007
• 年：2007
• 卷：72
• 期：10
• 页码：3976 - 3979
• 全文大小：83K
• 年卷期：v.72,no.10(May 11, 2007)
• ISSN：1520-6904

文摘

Tertiary aryl squaramides were synthesized by using coppercatalyzed C-N bond-formation with L-proline as the ligand.Symmetrical diaryl squaramides could be prepared in a one-pot reaction by using excess aryl bromide with varyingyields. Unsymmetrical derivatives were prepared by sequential arylation. Yields of the diarylated products were highlysensitive to steric effects.