Reaction-Based Two-Photon Probes for Mercury Ions: Fluorescence Imaging with Dual Optical Windows
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- 作者：Alla Sreenivasa Rao ; Dokyoung Kim ; Taejun Wang ; Ki Hean Kim ; Sekyu Hwang ; Kyo Han Ahn
- 刊名：Organic Letters
- 出版年：2012
- 出版时间：May 18, 2012
- 年：2012
- 卷：14
- 期：10
- 页码：2598-2601
- 全文大小：215K
- 年卷期：v.14,no.10(May 18, 2012)
- ISSN：1523-7052
文摘
For fluorescent imaging of mercury ions in living species, two-photon probes with dual optical windows are in high demand but remain unexplored. Several dithioacetals were evaluated, and a probe was found, which, upon reaction with mercury species, yielded a two-photon dye; this conversion accompanies ratiometric emission changes with a 97-nm shift, enabling fluorescent imaging of both the probe and mercury ions in cells by one- and two-photon microscopy for the first time.