A New Approach for the Synthesis of Hyperbranched N-Glycan Core Structures from Locust Bean Gum

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• 作者：Ravi Kumar H. V. ; Kentaro Naruchi ; Risho Miyoshi ; Hiroshi Hinou ; Shin-Ichiro Nishimura
• 刊名：Organic Letters
• 出版年：2013
• 出版时间：December 20, 2013
• 年：2013
• 卷：15
• 期：24
• 页码：6278-6281
• 全文大小：365K
• 年卷期：v.15,no.24(December 20, 2013)
• ISSN：1523-7052

文摘

A novel protocol for the synthesis of general N-glycan core structures was established by means of Man尾(1鈫?)Man peracetate derived from a naturally abundant locust bean gum as a key starting material. Phenyl (2-O-benzyl-4,6-O-benzylidine-尾-d-mannopyranosyl)-(1鈫?)-3,6-di-O-benzyl-2-azido-2-deoxy-1-thio-尾-d-glucopyranoside facilitated the synthesis of key intermediates leading to hyperbranched N-glycan core structures.