Novel Silver Tetrafluoroborate Catalyzed Electrophilic Cascade Cyclization Reaction: A Facile Approach to the Synthesis of Halo-Substituted Benzo[a]fluorenols

详细信息    查看全文

• 作者：Zhiyuan Chen ; Mengjing Zeng ; Jianjun Yuan ; Qin Yang ; Yiyuan Peng
• 刊名：Organic Letters
• 出版年：2012
• 出版时间：July 20, 2012
• 年：2012
• 卷：14
• 期：14
• 页码：3588-3591
• 全文大小：235K
• 年卷期：v.14,no.14(July 20, 2012)
• ISSN：1523-7052

文摘

A facile and novel silver tetrafluoroborate catalyzed electrophilic cascade cyclization reaction to generate halo-substituted benzo[a]fluorenols under mild conditions is disclosed. Good chemical selectivity and mild reaction conditions were involved in the transformation. The halide-containing benzo[a]fluorenols could be further elaborated via palladium-catalyzed cross-coupling reactions to introduce complexity.