Single-crystalline Li4Mn5O12 nanosticks were prepared by a simple method of adding MnSO4 to molten LiNO3 and NaNO3. FESEM and HRTEM investigations revealed that two-dimensional Li4Mn5O12 nanosticks were generated in large quantity. The results of dc and ac magnetization as well as magnetic hysteresis measurements suggest spin-glass-like behavior at 9.8 K. Furthermore, an exchange-bias effect is observed over the material in applied magnetic field of H ≤ 5 T.