文摘
A spectroscopic assay based on surface enhanced Raman scattering (SERS) using silver nanorod array substrates has been developed thatallows for rapid detection of trace levels of viruses with a high degree of sensitivity and specificity. This novel SERS assay can detect spectraldifferences between viruses, viral strains, and viruses with gene deletions in biological media. The method provides rapid diagnostics fordetection and characterization of viruses generating reproducible spectra without viral manipulation.