Ligand-Enabled 纬-C鈥揌 Olefination and Carbonylation: Construction of 尾-Quaternary Carbon Centers

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• 作者：Suhua Li ; Gang Chen ; Chen-Guo Feng ; Wei Gong ; Jin-Quan Yu
• 刊名：Journal of the American Chemical Society
• 出版年：2014
• 出版时间：April 9, 2014
• 年：2014
• 卷：136
• 期：14
• 页码：5267-5270
• 全文大小：340K
• 年卷期：v.136,no.14(April 9, 2014)
• ISSN：1520-5126

文摘

Monoselective 纬-C鈥揌 olefination and carbonylation of aliphatic acids has been accomplished by using a combination of a quinoline-based ligand and a weakly coordinating amide directing group. The reaction provides a new route for constructing richly functionalized all-carbon quaternary carbon centers at the 尾-position of aliphatic acids.