Palladium-Iminophosphine-Catalyzed Alkynylstannylation of Alkynes
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- 作者：Hiroto Yoshida ; Eiji Shirakawa ; Takuya Kurahashi ; Yoshiaki Nakao ; and Tamejiro Hiyama
- 刊名：Organometallics
- 出版年：2000
- 出版时间：December 25, 2000
- 年：2000
- 卷：19
- 期：26
- 页码：5671 - 5678
- 全文大小：111K
- 年卷期：v.19,no.26(December 25, 2000)
- ISSN：1520-6041
文摘
A palladium complex coordinated by an iminophosphine ligand was found to catalyze theaddition of alkynylstannanes to a carbon-carbon triple bond of various alkynes in moderateto good yields with exclusive syn selectivity. The alkynyl group in the stannanes was attachedmainly to the internal carbon of terminal alkynes, except for 1-alkyn-3-ones and alkynoates,where the alkynyl group was connected to the terminal carbon. Steric bulk of the ligandmarkedly influenced on the regioselectivity and reaction rate: an iminophosphine with abulkier imino moiety accelerated the alkynylstannylation with higher regioselectivity. Onthe basis of these observations, the mechanism of the present reaction is discussed.