Merging Photoredox with Palladium Catalysis: Decarboxylative ortho-Acylation of Acetanilides with 伪-Oxocarboxylic Acids under Mild Reaction Conditions

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• 作者：Chao Zhou ; Pinhua Li ; Xianjin Zhu ; Lei Wang
• 刊名：Organic Letters
• 出版年：2015
• 出版时间：December 18, 2015
• 年：2015
• 卷：17
• 期：24
• 页码：6198-6201
• 全文大小：381K
• ISSN：1523-7052

文摘

A room temperature decarboxylative ortho-acylation of acetanilides with 伪-oxocarboxylic acids has been developed via a novel Eosin Y with Pd dual catalytic system. This dual catalytic reaction shows a broad substrate scope and good functional group tolerance, and an array of ortho-acylacetanilides can be afforded in high yields under mild conditions.