International guideline development for the determination of death

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• 作者：Sam D. Shemie (1)
  Laura Hornby (1)
  Andrew Baker (1)
  Jeanne Teitelbaum (1)
  Sylvia Torrance (1)
  Kimberly Young (1)
  Alexander M. Capron (1)
  James L. Bernat (1)
  Luc Noel (1)
  
• 关键词：Death ; Brain death ; Circulatory death ; Cardiac death ; Organ donation ; Brain injury ; Cardiopulmonary resuscitation ; Autoresuscitation
• 刊名：Intensive Care Medicine
• 出版年：2014
• 出版时间：June 2014
• 年：2014
• 卷：40
• 期：6
• 页码：788-797
• 全文大小：
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  15. Hornby K, Hornby L, Shemie SD (2010) A systematic review of autoresuscitation after cardiac arrest. Crit Care Med 38(5):1246-253
  16. Wijdicks EF, Diringer MN (2004) Electrocardiographic activity after terminal cardiac arrest in neurocatastrophes. Neurology 62(4):673-74 CrossRef
  17. Sheth KN, Nutter T, Stein DM, Scalea TM, Bernat JL (2012) Autoresuscitation after asystole in patients being considered for organ donation. Crit Care Med 40(1):158-61 CrossRef
  18. Dhanani S, Hornby L, Ward R, Shemie S (2012) Variability in the determination of death after cardiac arrest: a review of guidelines and statements. J Intensive Care Med 27(4):238-52 CrossRef
  19. Moss J, Rockoff M (1980) EEG monitoring during cardiac arrest and resuscitation. JAMA 244(24):2750-751 ma.1980.03310240042022" target="_blank" title="It opens in new window">CrossRef
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• 作者单位：Sam D. Shemie (1)
  Laura Hornby (1)
  Andrew Baker (1)
  Jeanne Teitelbaum (1)
  Sylvia Torrance (1)
  Kimberly Young (1)
  Alexander M. Capron (1)
  James L. Bernat (1)
  Luc Noel (1)
  
  1. Canadian Blood Services and Division of Critical Care, Montreal Children’s Hospital, McGill University Health Centre, 2300 Tupper Street room C-806, Montreal, QC, H3H 1P3, Canada
  
• ISSN：1432-1238

文摘

Introduction and Methods This report summarizes the results of the first phase in the development of international guidelines for death determination, focusing on the biology of death and the dying process, developed by an invitational forum of international content experts and representatives of a number of professional societies. Results and Conclusions Precise terminology was developed in order to improve clarity in death discussion and debate. Critical events in the physiological sequences leading to cessation of neurological and/or circulatory function were constructed. It was agreed that death determination is primarily clinical and recommendations for preconditions, confounding factors, minimum clinical standards and additional testing were made. A single operational definition of human death was developed: ‘the permanent loss of capacity for consciousness and all brainstem functions, as a consequence of permanent cessation of circulation or catastrophic brain injury- In order to complete the project, in the next phase, a broader group of international stakeholders will develop clinical practice guidelines, based on comprehensive reviews and grading of the existing evidence.