Online autofluorescence measurements during selective RPE laser treatment
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- 作者：Carsten Framme ; Georg Schüle ; Johann Roider ; Reginald Birngruber and Ralf Brinkmann
- 刊名：Graefe's Archive for Clinical and Experimental Ophthalmology
- 出版年：2004
- 出版时间：October 2004
- 年：2004
- 卷：242
- 期：10
- 页码：863-869
- 全文大小：261 KB
- 刊物类别：Medicine
- 刊物主题：Medicine & Public Health
Ophthalmology - 出版者：Springer Berlin / Heidelberg
- ISSN：1435-702X
文摘
Background Fundus autofluorescence (AF) is derived from the lipofuscin contained by the retinal pigment epithelial cells. Using a scanning laser ophthalmoscope, two-dimensional AF measurements of the ocular fundus can be achieved. Directly after conventional photocoagulation and also after selective RPE laser treatment (SRT) with ophthalmoscopically non-visible laser lesions, irradiated areas reveal reduced AF, indicating RPE damage. Since the green treatment laser beam could also be used for AF excitation, the aim of this study was to evaluate whether absolute measurements of AF can be performed, and also possible changes in AF detected, online during SRT.