A common polymorphism rs1800247 in osteocalcin gene was associated with serum osteocalcin levels, bone mineral density, and fracture: the Shanghai Changfeng Study

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• 作者：Y. Ling ; X. Gao ; H. Lin ; H. Ma ; B. Pan ; J. Gao
• 关键词：Bone mineral density ; Fracture ; Osteocalcin gene ; Polymorphism ; rs1800247 ; Serum osteocalcin
• 刊名：Osteoporosis International
• 出版年：2016
• 出版时间：February 2016
• 年：2016
• 卷：27
• 期：2
• 页码：769-779
• 全文大小：338 KB
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• 作者单位：Y. Ling (1)
  X. Gao (1)
  H. Lin (1)
  H. Ma (2)
  B. Pan (3)
  J. Gao (4)
  
  1. Department of Endocrinology and Metabolism, Zhongshan Hospital, Fudan University, No. 180 Fenglin Road, 200032, Shanghai, China
  2. Department of Geriatrics, Zhongshan Hospital, Fudan University, No. 180 Fenglin Road, 200032, Shanghai, China
  3. Department of Laboratory Medicine, Zhongshan Hospital, Fudan University, No. 180 Fenglin Road, 200032, Shanghai, China
  4. Department of Clinical Nutrition, Zhongshan Hospital, Fudan University, No. 180 Fenglin Road, 200032, Shanghai, China
  
• 刊物类别：Medicine
• 刊物主题：Medicine & Public Health
  Orthopedics
  Gynecology
  Endocrinology
  Rheumatology
  
• 出版者：Springer London
• ISSN：1433-2965

文摘

Summary We evaluated the relationship between a common polymorphism rs1800247 in osteocalcin gene and serum osteocalcin levels, bone mineral density and fracture in Chinese. This was a population-based cross-sectional study. We demonstrated that rs1800247 was associated with bone mineral density and fracture in men and serum osteocalcin levels in women.