Effects of milnacipran and fluvoxamine on hyperemotional behaviors and the loss of tryptophan hydroxylase-positive cells in olfactory bulbectomized rats

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• 作者：Akiyoshi Saitoh ; Kazumasa Yamaguchi ; Yoshimi Tatsumi ; Hiroyasu Murasawa ; Akiko Nakatani ; Noritaka Hirose ; Misa Yamada ; Mitsuhiko Yamada and Junzo Kamei
• 关键词：Olfactory bulbectomy ; Milnacipran ; Fluvoxamine ; Tryptophan hydroxylase
• 刊名：Psychopharmacology
• 出版年：2007
• 出版时间：May, 2007
• 年：2007
• 卷：191
• 期：4
• 页码：857-865
• 全文大小：328 KB
• 刊物类别：Biomedical and Life Sciences
• 刊物主题：Biomedicine
  Pharmacology and Toxicology
  Psychiatry
  
• 出版者：Springer Berlin / Heidelberg
• ISSN：1432-2072

文摘

Rationale It has been reported that many of the behavioral and serotonergic neuronal changes observed in olfactory bulbectomy (OBX) were improved by subchronic administration of a variety of antidepressants.