Social stress-escalated intermittent alcohol drinking: modulation by CRF-R1 in the ventral tegmental area and accumbal dopamine in mice

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• 作者：Lara S. Hwa ; Elizabeth N. Holly ; Joseph F. DeBold ; Klaus A. Miczek
• 关键词：Alcohol ; Intermittent ; Social defeat stress ; Ventral tegmental area ; CRF ; R1 ; CRF ; R2 ; Dopamine ; Nucleus accumbens ; Microdialysis
• 刊名：Psychopharmacology
• 出版年：2016
• 出版时间：February 2016
• 年：2016
• 卷：233
• 期：4
• 页码：681-690
• 全文大小：829 KB
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• 作者单位：Lara S. Hwa (1)
  Elizabeth N. Holly (1)
  Joseph F. DeBold (1)
  Klaus A. Miczek (1) (2)
  
  1. Psychology Department, Tufts University, 530 Boston Avenue, Medford, MA, 02155, USA
  2. Neuroscience Department, Tufts University, Boston, MA, 02111, USA
  
• 刊物类别：Biomedical and Life Sciences
• 刊物主题：Biomedicine
  Pharmacology and Toxicology
  Psychiatry
  
• 出版者：Springer Berlin / Heidelberg
• ISSN：1432-2072

文摘

Rationale Excessive alcohol (EtOH) drinking is difficult to model in animals despite the extensive human literature demonstrating that stress increases EtOH consumption.