Additional perspectives on chronic kidney disease of unknown aetiology (CKDu) in Sri Lanka -lessons learned from the WHO CKDu population prevalence study

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• 作者：Jennifer Hoponick Redmon ; Myles F Elledge ; Donna S Womack…
• 关键词：Chronic kidney disease ; Chronic kidney disease of unknown aetiology ; Environmental nephrotoxins ; Sri Lanka ; Heavy metals ; Agrochemicals ; Cadmium
• 刊名：BMC Nephrology
• 出版年：2014
• 出版时间：December 2014
• 年：2014
• 卷：15
• 期：1
• 全文大小：322 KB
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• 刊物主题：Nephrology; Internal Medicine;
• 出版者：BioMed Central
• ISSN：1471-2369

文摘

The recent emergence of an apparently new form of chronic kidney disease of unknown aetiology (CKDu) has become a serious public health crisis in Sri Lanka. CKDu is slowly progressive, irreversible, and asymptomatic until late stages, and is not attributable to hypertension, diabetes, or other known aetiologies. In response to the scope and severity of the emerging CKDu health crisis, the Sri Lanka Ministry of Health and the World Health Organization initiated a collaborative research project from 2009 through 2012 to investigate CKDu prevalence and aetiology. The objective of this paper is to discuss the recently published findings of this investigation and present additional considerations and recommendations that may enhance subsequent investigations designed to identify and understand CKDu risk factors in Sri Lanka or other countries.