Update of Wnt signaling in implantation and decidualization

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• 作者：Qian Zhang ; Junhao Yan
• 关键词：β ; Catenin ; Decidualization ; Implantation ; Wnt ligands ; Wnt signaling
• 刊名：Reproductive Medicine and Biology
• 出版年：2016
• 出版时间：April 2016
• 年：2016
• 卷：15
• 期：2
• 页码：95-105
• 全文大小：1,996 KB
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• 作者单位：Qian Zhang (1) (2) (3) (4)
  Junhao Yan (1) (2) (3) (4)
  
  1. Center for Reproductive Medicine, Shandong Provincial Hospital Affiliated to Shandong University, Jinan, 250021, China
  2. National Research Center for Assisted Reproductive Technology and Reproductive Genetics, Jinan, China
  3. The Key Laboratory for Reproductive Endocrinology of Ministry of Education, Jinan, China
  4. Shandong Provincial Key Laboratory of Reproductive Medicine, Jinan, China
  
• 刊物主题：Reproductive Medicine; Gynecology; Urology/Andrology;
• 出版者：Springer Japan
• ISSN：1447-0578

文摘

Embryonic development into an implantation-competent blastocyst, synchronized uterine transformation into a receptive stage, and an intimate cross-talk between the activated blastocyst and the receptive uterus are essential for successful implantation, and therefore for subsequent pregnancy outcome. Evidence accumulating during recent years has underlined the importance of the Wnt signaling pathway in mammalian implantation and decidualization. Herein, this review focuses on the current state of knowledge regarding Wnt signaling in multiple implantation and decidualization events: pre-implantation embryo development, blastocyst activation for implantation, uterine development, and decidualization.