Interassay reproducibility of myocardial perfusion gated SPECT in patients with atrial fibrillation

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• 作者：Santiago Aguadé-Bruix MD (1)
  Guillermo Romero-Farina MD ; PhD ; FESC (2)
  Gemma Cuberas-Borros PhD (2)
  Marta Milà-Lopez MD (1)
  Virginia Pubul-Nú?ez MD (3)
  Rosa Siurana-Escuer MD ; PhD (4)
  David García-Dorado MD ; PhD ; FESC (2)
  Jaume Candell-Riera MD ; PhD ; FESC (2)
  
• 关键词：Atrial fibrillation ; gated ; SPECT ; interassay reproducibility ; myocardial perfusion imaging
• 刊名：Journal of Nuclear Cardiology
• 出版年：2010
• 出版时间：June 2010
• 年：2010
• 卷：17
• 期：3
• 页码：450-458
• 全文大小：420KB
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• 作者单位：Santiago Aguadé-Bruix MD (1)
  Guillermo Romero-Farina MD, PhD, FESC (2)
  Gemma Cuberas-Borros PhD (2)
  Marta Milà-Lopez MD (1)
  Virginia Pubul-Nú?ez MD (3)
  Rosa Siurana-Escuer MD, PhD (4)
  David García-Dorado MD, PhD, FESC (2)
  Jaume Candell-Riera MD, PhD, FESC (2)
  
  1. Department of Nuclear Medicine, Hospital Universitari Vall d’Hebron, Universitat Autònoma de Barcelona, Passeig Vall d’Hebron, 119-129, 08035, Barcelona, Spain
  2. Cardiology Department, Hospital Universitari Vall d’Hebron, Universitat Autònoma de Barcelona, Barcelona, Spain
  3. Department of Nuclear Medicine, Complejo Universitario Hospitalario, Santiago de Compostela, Spain
  4. Department of Nuclear Medicine, Hospital Universitari Joan XXIII, Tarragona, Spain
  

文摘

Aim The aim of this study was to assess interassay reproducibility of myocardial perfusion gated-SPECT for calculation of end-diastolic volume (EDV), end-systolic volume (ESV), and left ventricular ejection fraction (LVEF) in patients with atrial fibrillation (AF). Methods One hundred and fifteen consecutive patients with AF from three participating hospitals (mean age 68.9?years, 39 women) were included in the study. All patients underwent two image gated acquisitions at rest with a 30?minute interval between them. Quantitative data were obtained using the QGS and ECT software algorithms. Results Heart rate was similar in both studies: 74.94?±?15.2 vs 73.03?±?15.57. QGS yielded an LVEF of 54.4%/53.8%, an EDV of 100?mL/101.5?mL, and an ESV of 51?mL/52.3?mL; and ECT showed an LVEF of 63.6%/62.9%, an EDV of 125.8?mL/127.4?mL and ESV of 54.1?mL/56.3?mL. Correlation between the two acquisitions was high (>0.948) for both methods for LVEF, EDV and ESV. Regression and Bland-Altman graphics showed a good agreement between all parameters. Interassay variation coefficients for each method (QGS/ECT) were 5.29% vs 4.83% for LVEF, 4.94% vs 5.17% for EDV, and 9.94% vs 12.78% for ESV. Conclusions Interassay reproducibility of LVEF and EDV with gated-SPECT in patients with AF is good, whereas for ESV it is suboptimal, particularly when ESV is small.