文摘
The phenomena of auto-positive end-expiratory pressure (auto-PEEP) and hyperinflation in patients under mechanical ventilation have been known for over 40 years. In this context, airway obstruction, insufficient expiration times and inadequate respiratory pressures play important roles. The negative effects of auto-PEEP and hyperinflation are complex and include barotrauma, impairment of hemodynamics, asynchrony between patient and ventilator and dyspnea. In addition to the definition of signs of hyperinflation and the underlying pathophysiology, this article describes the relevant methods applicable at the bedside for determination of auto-PEEP and air trapping. The most important steps to prevent hyperinflation in mechanically ventilated patients are also explained.