A LC-MS/MS Method for Quantifying Adenosine, Guanosine and Inosine Nucleotides in Human Cells
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- 作者：Leah C. Jimmerson ; Lane R. Bushman ; Michelle L. Ray…
- 关键词：KEY WORDSanalytical method ; dried blood spots ; intracellular quantification ; LC ; MS/MS ; purine nucleotides
- 刊名：Pharmaceutical Research
- 出版年：2017
- 出版时间：January 2017
- 年：2017
- 卷：34
- 期：1
- 页码：73-83
- 全文大小：
- 刊物类别：Biomedical and Life Sciences
- 刊物主题：Pharmacology/Toxicology; Pharmacy; Biochemistry, general; Medical Law; Biomedical Engineering;
- 出版者：Springer US
- ISSN：1573-904X
- 卷排序：34
文摘
PurposeTo develop and validate a method for the simultaneous measurement of adenosine, guanosine, and inosine derived from mono (MP) and triphosphate (TP) forms in peripheral blood mononuclear cells (PBMCs), red blood cells (RBCs) and dried blood spots (DBS).