Osteolysen der Mandibula

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• 作者：S. Grunert ; M. Ermer ; P. Voss ; R. Schmelzeisen
• 关键词：Multiples Myelom ; Plasmozytom ; Osteolysen ; Mandibula ; Wurzelresorption ; Multiple myeloma ; Plasmacytoma ; Osteolysis ; Mandible ; Root resorption
• 刊名：Der MKG-Chirurg
• 出版年：2015
• 出版时间：February 2015
• 年：2015
• 卷：8
• 期：1
• 页码：31-34
• 全文大小：587 KB
• 参考文献：1. DelBalso AM (1995) Lesions of the jaws. Semin Ultrasound CT MR 16:487-12 rnal" href="http://dx.doi.org/10.1016/S0887-2171(06)80022-3" target="_blank" title="It opens in new window">CrossRef r> 2. Epstein JB, Voss NJ, Stevenson-Moore P (1984) Maxillofacial manifestations of multiple myeloma. An unusual case and review of the literature. Oral Surg Oral Med Oral Pathol 57:267-71 rnal" href="http://dx.doi.org/10.1016/0030-4220(84)90182-8" target="_blank" title="It opens in new window">CrossRef r> 3. Furutani M, Ohnishi M, Tanaka Y (1994) Mandibular involvement in patients with multiple myeloma. J Oral Maxillofac Surg 52:23-5 rnal" href="http://dx.doi.org/10.1016/0278-2391(94)90007-8" target="_blank" title="It opens in new window">CrossRef r> 4. Lambertenghi-Deliliers G, Bruno E, Cortelezzi A et al (1988) Incidence of jaw lesions in 193 patients with multiple myeloma. Oral Surg Oral Med Oral Pathol 65:533-37 rnal" href="http://dx.doi.org/10.1016/0030-4220(88)90135-1" target="_blank" title="It opens in new window">CrossRef r> 5. Locke FL, Morgan GJ (2012) What is the evidence for the use of bisphosphonate therapy in newly diagnosed multiple myeloma patients lacking bone disease? Hematology Am Soc Hematol Educ Program 2012:350-53 r> 6. Mozaffari E, Mupparapu M, Otis L (2002) Undiagnosed multiple myeloma causing extensive dental bleeding: report of a case and review. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 94:448-53 rnal" href="http://dx.doi.org/10.1067/moe.2002.125201" target="_blank" title="It opens in new window">CrossRef r> 7. Stoopler ET, Vogl DT, Stadtmauer EA (2007) Medical management update: multiple myeloma. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 103:599-09 rnal" href="http://dx.doi.org/10.1016/j.tripleo.2006.10.026" target="_blank" title="It opens in new window">CrossRef r> 8. Witt C, Borges AC, Klein K et al (1997) Radiographic manifestations of multiple myeloma in the mandible: a retrospective study of 77 patients. J Oral Maxillofac Surg 55:450-53 (discussion 4-) rnal" href="http://dx.doi.org/10.1016/S0278-2391(97)90687-X" target="_blank" title="It opens in new window">CrossRef r> 9. Troeltzsch M, Oduncu F, Mayr D et al (2014) Root resorption caused by jaw infiltration of multiple myeloma: report of a case and literature review. J Endod 40:1260-264 rnal" href="http://dx.doi.org/10.1016/j.joen.2013.12.030" target="_blank" title="It opens in new window">CrossRef r>
• 刊物主题：Oral and Maxillofacial Surgery; Plastic Surgery; Otorhinolaryngology; Head and Neck Surgery; Dentistry;
• 出版者：Springer Berlin Heidelberg
• ISSN：1865-9667

文摘

Multiple myeloma is an aggressive B-cell non-Hodgkin’s lymphoma with diffuse or multilocular bone marrow infiltration by myeloma cells. The etiology so far is unknown. Nonspecific symptoms include B symptoms, bone pain, renal dysfunction and hematopoietic changes. Radiographical changes with osteolysis are typically seen in the skull, pelvis and ribs. Pathological fractures occur frequently. The first manifestation in the maxillofacial region is rare. If unclear bone pain and painful osteolytic lesions in the jaws are reported, a more accurate radiological and pathological diagnosis should be performed to exclude solitary plasmacytoma or multiple myeloma.