摘要
Objective
<p>To evaluate the effect of body mass index (BMI) on PSA in northeast Mexican patients included in prostate cancer (Pca) early detection screening campaigns offered by our institution.Material and methods
<p>One hundred and ninety seven patients came voluntarily to our Pca early detection screening campaigns. Exclusion criteria: PSA >10 ng/dl, patients on 5-伪 Reductase inhibitors or hormonal replacement. Overweight and obesity were considered when BMI was between 25-29.9 and 鈮?0 kg/mp>2p> respectively. Simple linear and multiple regression were used in the statistical analysis. Mean and standard deviation were utilized to evaluate spread and normal distribution. P values <0.05 were considered statistically significant.Results
<p>One hundred and fifty two patients were included in this study. Forty four percent (83) and 30.3%(46) presented with overweight and obesity, respectively. Mean BMI was 28.16 kg/mp>2p> (SD 1.77). A statistically significant negative effect of BMI on PSA was observed in the linear regression. This effect persisted when adjusted for age in the multiple regression model. A decrease of 0.085 ng/dl for every unit of BMI (p <0.001) was observed in the simple linear regression. This value was 0.07 in the multiple regression (p = 0.006)Conclusions
<p>A higher negative effect of BMI on PSA was found in comparison to published literature. A higher proportion of patients with BMI >25 kg/mp>2p> than the national mean was observed. A multicentric national study is needed in order to challenge these results.
