Lithium–halogen exchange reaction using microreaction technology
- 作者：Jaehoon Choe ; Jung Hyun Seo ; Youngwoon Kwon ; Kwang Ho Song
- 关键词：Microreaction technology ; Bromonaphthalene ; Electron transport layer
- 刊名：Chemical Engineering Journal
- 出版年：2008
- 期刊代码：16_13858947
- 类别：ce
- 出版时间：15 January 2008
- 卷：135
- 期：Supplement 1
- 页码：S17-S20
- 文件大小：260 K
摘要
A two-stage continuous microreactor system was use to synthesize the materials for an organic light emitting diode. The split and recombine type of micromixers were suitable for the two-stage reaction including lithium-bromo exchange reaction. The two-stage synthesis was carried out under non-cryogenic conditions by taking full advantage of microstructured reaction systems. In a first stage, the unstable intermediate, naphthyl lithium was synthesized with maximum yield and consumed immediately in the second stage micromixer. The naphthyl-substituted anthracene was obtained with 97%purity.