• 作者：J.C. Portilla Cuenca^a ; ^{portilla7819@yahoo.es} ; J.M. Ramí ; rez-Moreno^a ; L. Ferná ; ndez de Alarc&#243 ; n^b ; I. Garcí ; a  ; Castañ ; &#243 ; n^a ; M. Caballero Muñ ; oz^a ; A. Serrano Cabrera^a ; A. Falc&#243 ; n Garcí ; a^a ; M. G&#243 ; mez Gutierrez^a ; I. Casado Naranjo^a ; ^c
• 关键词：Angiografí ; a cerebral ; Aterosclerosis carotidea ; Doppler ; Estenosis extracraneal ; Estudio ultrasonográ ; fico
• 刊名：Neurolog铆a
• 出版年：2010
• 期刊代码：pca262_02134853
• 类别：med
• 出版时间：July-August 2010
• 卷：25
• 期：6
• 页码：357-363
• 文件大小：155 K

lass="h4">Introduction

Arteriosclerosis of the extra-cranial arteries is believed to be responsible for almost one-third of all ischaemic strokes. The sound diagnosis of the degree of stenosis is essential in deciding the best therapeutic strategy. Although cerebral angiography is considered the reference technique, ultrasound study (UST) is a more readily available, non-invasive and well-established procedure for quantifying carotid stenosis. However, on being a dependent exploratory technique, it is recommended that each laboratory validates its results against angiography.

lass="h4">Objetives

To establish the validity of the neuro-ultrasound study in our laboratory for use in the diagnosis of extracranial atheromatous disease, and determine its capacity to quantify the degree of stenosis in the internal carotid artery.

lass="h4">Material and methods

A retrospective study of patients with extracranial carotid atheromatous disease, in whom the diagnostic process was carried out with carotid ultrasound as well as supra-aortic trunk digital-subtraction angiography.

lass="h4">Results

A total of 254 carotids were evaluated and the degree of stenosis being classified into > 50%, 70-99%and 100%. The UST for the first group had a sensitivity (Se) of 97%, a specificity (Sp) of 90%, a positive predictive value (PPV) of 94.6%and a negative predictive value (NPV) of 94.2%. The second group had an Se of 96.4%, Sp 93%; PPV 94.4%and NPV 95.4%. The respective values for carotid occlusion were, 85%, 96.8%, 80%and 97.8%.

lass="h4">Conclusions

Our data validates the ability of UST performed in our Laboratory to diagnose the degree of carotid stenosis.