- 作者：Inmaculada Ruiz Molina ; macuap@hotmail.com ; Teresa Gonzá ; lez Serrano ; Eduardo Solí ; s Garcí ; a
- 关键词：Ovario ; Tumor de cé ; lulas de Sertoli-Leydig ; Elementos heteró ; logos
- 刊名：Revista Espa帽ola de Patolog铆a
- 出版年：2010
- 期刊代码：pca318_16998855
- 类别：med
- 出版时间：July-September 2010
- 卷：43
- 期：3
- 页码：151-154
- 文件大小：2472 K
Introduction
Sertoli-Leydig cell tumours (SLCT) of the ovary are rare, accounting for only 1%of all sex cord-stromal tumours and are formed by Sertoli and Leydig cells and/or fibroblasts in different proportions and various degrees of differentiation. Sometimes they may contain heterologous elements, such as mucinous epithelium, cartilage, skeletal muscle and/or carcinoid and therefore should be considered in the differential diagnosis of various types of tumours.
Methods
The clinical, histological and immunohistochemical features of a case of Sertoli Leydig tumour of the ovary are presented and the literature is reviewed. Sections were stained with hematoxylin-eosin and immunohistochemistry using the streptavidin-biotin-peroxidase method for CD56, S-100 protein, cytokeratin (AE1/AE and 20), CEA, vimentin, inhibin, calretinin and CDX2 was performed.
Results and conclusions
The tumour had a characteristic appearance, being composed mainly of stromal cells with few Sertoli cell tubules, admixed with Leydig cells. Immunohistochemistry confirmed the diagnosis.