A10(PO4)6(OH)2 (A = Ca and Sr)-supported Pt catalysts were prepared and their catalytic activity in NO reduction were investigated. The Sr10(PO4)6(OH)2-supported catalyst had high catalytic activity in the C3H6–NO–O2 reaction; the activity was higher than that of the γ-Al2O3-supported catalyst at 300 掳C. The basicity of the apatite supports would affect the chemical state of Pt on catalyst, resulting in promotion of NO reduction.