CT与MRI融合技术的颅内肿瘤应用研究
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摘要
CT及MRI融合的目的是增强图像显示的直观效果,提高对对疾病诊断的准确性。利用CT及MRI对于机体的骨质、钙化和软组织的分辨率互补性的特点,将同一病例的CT、MRI图像进行融合,从而更精准的进行肿瘤的定位。融合之后的图像不仅反映出硬组织,还正确清晰地反映出其边界,为颅内肿瘤的诊断奠定了基础。CT与MRI图像融合既能弥补各自的不足之处,也能在形态和功能上发挥协同作用,从而更精准地对颅脑肿瘤定位和边界分割,为临床的肿瘤放射治疗提供影像学支持。
The purpose of CT and MRI fusion is to enhance the visual effect of image display and improve the accuracy of diagnosis. Using the complementary characteristics of resolution of the bone, calcification and soft tissue of the body, same case CT and MRI images were fused, so that the location of the tumor is more accurate. After fusion, the fused image not only reflects the hard tissue, but also reflects the boundary of the tissue, It is the intracranial tumors diagnosis foundation. CT and MRI image fusion can not only make up for their shortcomings, but also can play a synergistic role in morphology and function, more accurate brain tumor location and boundary segmentation, provide imaging support for the clinical treatment of radiation oncology.
The purpose of CT and MRI fusion is to enhance the visual effect of image display and improve the accuracy of diagnosis. Using the complementary characteristics of resolution of the bone, calcification and soft tissue of the body, same case CT and MRI images were fused, so that the location of the tumor is more accurate. After fusion, the fused image not only reflects the hard tissue, but also reflects the boundary of the tissue, It is the intracranial tumors diagnosis foundation. CT and MRI image fusion can not only make up for their shortcomings, but also can play a synergistic role in morphology and function, more accurate brain tumor location and boundary segmentation, provide imaging support for the clinical treatment of radiation oncology.
引文
[1]董默,苏奎,周志尊,周鸿锁.生物医学工程专业《医学图像处理》实践教学的改革[J].软件,2017,38(2):37-41.
[2]李凯,曾庆劲,郑荣琴,苏中振,贺需旗等.CT/MR图像融合评价肝癌消融的安全边界[J].中国医学影像技术,2012,25(12):2189-2192.
[3]吴涛,崔坤炜.SPECT/CT融合显像在临床核医学中的应用现状[J].中国医学影像技术,2016,32(2):306-308.
[4]尚靳,郭启勇,孙洪赞,辛军.CT、MRI与PET融合显像评价宫颈癌分期及淋巴结转移中的应用进展[J].中国医学影像技术,2016,32(5):795-798.
[5]Wang Y,Liu ZY,Dou WC,Ma WB,Wang RZ,Guo Y.Application of Preoperative CT/MRI Image Fusion in Target Positioning for Deep Brain Stimulation[J].Chin Med Sci J,2016,31(3):161-167.
[6]Geevarghese R,O’Gorman Tuura R,Lumsden DE,Samuel M,Ashkan K.Registration Accuracy of CT/MRI Fusion for Localisation of Deep Brain Stimulation Electrode Position:An Imaging Study and Systematic Review[J].Stereotact Funct Neurosurg,2016,94(3):159-63.
[7]Chavan SS,Mahajan A,Talbar SN,Desai S,Thakur M,D’cruz A.Nonsubsampled rotated complex wavelet transform(NSRCx WT)for medical image fusion related to clinical aspects in neurocysticercosis[J].Comput Biol Med,2017,81:64-78.
[8]Barnaure I,Pollak P,Momjian S,Horvath J,Lovblad KO.Evaluation of electrode position in deep brain stimulation by image fusion(MRI and CT)[J].Neuroradiology.2015,57(9):903-910.
[9]Prada F,Del Bene M,Mattei L,Lodigiani L,De Beni S,Kolev V,Vetrano I,Solbiati L,Sakas G,Di Meco F.Preoperative magnetic resonance and intraoperative ultrasound fusion imaging for real-time neuronavigation in brain tumor surgery[J].Ultraschall Med,2015,36(2):174-86.
[10]Djan.I,Petrovi.B,Erak.M,Nikoli.I,Luci.S.Radiotherapy treatment planning:benefits of CT-MR image registration and fusion in tumor volume delineation[J].Vojnosanit Pregl,2013,70(8):735-9.
[11]Fiorentino A,Caivano R,Pedicini P,Fusco V.Clinical target volume definition for glioblastoma radiotherapy planning:magnetic resonance imaging and computed tomography[J].Clin Transl Oncol,2013,15(9):754-8.
[12]O’Gorman RL,Jarosz JM,Samuel M,Clough C,Selway RP,Ashkan K.CT/MR image fusion in the postoperative assessment of electrodes implanted for deep brain stimulation[J].Stereotact Funct Neurosurg,2009,87(4):205-10.
[13]Kuhn SA,Romeike B,Walter J,Kalff R,Reichart R.Multiplanar MRI-CT fusion neuronavigation-guided serial stereotactic biopsy of human brain tumors:proof of a strong correlation between tumor imaging and histopathology by a new technical approach[J].J Cancer Res Clin Oncol,2009,135(9):1293-302.
[14]白人驹主编,医学影像学,第二版.北京:人民卫生出版社,2010.
[2]李凯,曾庆劲,郑荣琴,苏中振,贺需旗等.CT/MR图像融合评价肝癌消融的安全边界[J].中国医学影像技术,2012,25(12):2189-2192.
[3]吴涛,崔坤炜.SPECT/CT融合显像在临床核医学中的应用现状[J].中国医学影像技术,2016,32(2):306-308.
[4]尚靳,郭启勇,孙洪赞,辛军.CT、MRI与PET融合显像评价宫颈癌分期及淋巴结转移中的应用进展[J].中国医学影像技术,2016,32(5):795-798.
[5]Wang Y,Liu ZY,Dou WC,Ma WB,Wang RZ,Guo Y.Application of Preoperative CT/MRI Image Fusion in Target Positioning for Deep Brain Stimulation[J].Chin Med Sci J,2016,31(3):161-167.
[6]Geevarghese R,O’Gorman Tuura R,Lumsden DE,Samuel M,Ashkan K.Registration Accuracy of CT/MRI Fusion for Localisation of Deep Brain Stimulation Electrode Position:An Imaging Study and Systematic Review[J].Stereotact Funct Neurosurg,2016,94(3):159-63.
[7]Chavan SS,Mahajan A,Talbar SN,Desai S,Thakur M,D’cruz A.Nonsubsampled rotated complex wavelet transform(NSRCx WT)for medical image fusion related to clinical aspects in neurocysticercosis[J].Comput Biol Med,2017,81:64-78.
[8]Barnaure I,Pollak P,Momjian S,Horvath J,Lovblad KO.Evaluation of electrode position in deep brain stimulation by image fusion(MRI and CT)[J].Neuroradiology.2015,57(9):903-910.
[9]Prada F,Del Bene M,Mattei L,Lodigiani L,De Beni S,Kolev V,Vetrano I,Solbiati L,Sakas G,Di Meco F.Preoperative magnetic resonance and intraoperative ultrasound fusion imaging for real-time neuronavigation in brain tumor surgery[J].Ultraschall Med,2015,36(2):174-86.
[10]Djan.I,Petrovi.B,Erak.M,Nikoli.I,Luci.S.Radiotherapy treatment planning:benefits of CT-MR image registration and fusion in tumor volume delineation[J].Vojnosanit Pregl,2013,70(8):735-9.
[11]Fiorentino A,Caivano R,Pedicini P,Fusco V.Clinical target volume definition for glioblastoma radiotherapy planning:magnetic resonance imaging and computed tomography[J].Clin Transl Oncol,2013,15(9):754-8.
[12]O’Gorman RL,Jarosz JM,Samuel M,Clough C,Selway RP,Ashkan K.CT/MR image fusion in the postoperative assessment of electrodes implanted for deep brain stimulation[J].Stereotact Funct Neurosurg,2009,87(4):205-10.
[13]Kuhn SA,Romeike B,Walter J,Kalff R,Reichart R.Multiplanar MRI-CT fusion neuronavigation-guided serial stereotactic biopsy of human brain tumors:proof of a strong correlation between tumor imaging and histopathology by a new technical approach[J].J Cancer Res Clin Oncol,2009,135(9):1293-302.
[14]白人驹主编,医学影像学,第二版.北京:人民卫生出版社,2010.