2246例老年血脂异常患者高血压患病率及相关因素分析
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摘要
目的研究老年血脂异常患者的高血压患病现状和影响因素。方法对北京大学医院2015年2 246名老年血脂异常患者体检数据进行数据分析,采用相关分析和多元Logistic逐步回归等方法对其高血压患病率的相关因素进行分析。结果老年血脂异常患者的高血压患病率为46.84%,其中总胆固醇(TC)过高、三酰甘油(TG)过高、低密度脂蛋白胆固醇(LDL-C)过高和高密度脂蛋白胆固醇(HDL-C)偏低的老年人高血压患病率为47.64%、50.17%、42.28%和47.99%。高血压患病率随年龄增长有上升趋势,性别分布差异不明显。多元Logistic回归表明,高龄(OR=1.060)、超重或肥胖(OR=1.368)及患糖尿病(OR=1.653)的老年人更易患高血压(P<0.01)。结论高龄、超重或肥胖及患糖尿病是老年血脂异常患者患高血压的危险因素。
Objective To investigate the prevalence status quo and influencing factors of hypertension among older adults with dyslipidemia.Methods The data of physical examination in 2 246 elderly patients with dyslipidemia from Peking University Hospital in 2015 were analyzed.The correlation factors of hypertension prevalence among elderly patients with dyslipidemia were investigated by adopting the correlation analysis and multiple Logistic regression method.Results The prevalence rate of hypertension among elderly patients with dyslipidemia was 46.84%,among which the percentages of elderly patients with high TC,high TG,high LDL-C and low HDL-C were 47.64%,50.17%,42.28% and 47.99% respectively.The hypertension prevalence rate showed an increasing trend as age increases,and gender differences were not obvious.The multiple Logistic regression showed that the elderly patients with advanced age(OR=1.060),overweight or obesity(OR=1.368)and diabetes(OR=1.653)were more likely to suffer from hypertension(P<0.01).Conclusion Advanced age,overweight or obesity and diabetes are the risk factors of hypertension among elderly patients with dyslipidemia.
Objective To investigate the prevalence status quo and influencing factors of hypertension among older adults with dyslipidemia.Methods The data of physical examination in 2 246 elderly patients with dyslipidemia from Peking University Hospital in 2015 were analyzed.The correlation factors of hypertension prevalence among elderly patients with dyslipidemia were investigated by adopting the correlation analysis and multiple Logistic regression method.Results The prevalence rate of hypertension among elderly patients with dyslipidemia was 46.84%,among which the percentages of elderly patients with high TC,high TG,high LDL-C and low HDL-C were 47.64%,50.17%,42.28% and 47.99% respectively.The hypertension prevalence rate showed an increasing trend as age increases,and gender differences were not obvious.The multiple Logistic regression showed that the elderly patients with advanced age(OR=1.060),overweight or obesity(OR=1.368)and diabetes(OR=1.653)were more likely to suffer from hypertension(P<0.01).Conclusion Advanced age,overweight or obesity and diabetes are the risk factors of hypertension among elderly patients with dyslipidemia.
引文
[1]刘竟芳,陈哲,杨非柯,等.长沙市老年人血脂异常分布及其影响因素[J].中南大学学报(医学版),2014,39(8):797-801.
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[8]中国成人血脂异常防治指南制订联合委员会.中国成人血脂异常防治指南[J].中华心血管病杂志,2007,35(5):390-409.
[9]1999World Health Organization.International Society of Hypertension guidelines for the management of hypertension[J].Blood Pressure Supp1,1999(8):9-43.
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[11]王继光.老年高血压现状与问题[J].中国循环杂志,2017,22(11):1049-1051.
[12]谢张伟,方柯,邹伟,等.某高校教职工高血压现状调查[J].保健医学研究与实践,2012,9(3):14-15.
[13]熊有爱.404例40岁以上教职工血脂异常情况分析[J].江西教育学院学报,2010,31(3):82-83.
[14]PINTO E.Blood pressure and ageing[J].Post Med J,2007,83(976):109-114.
[15]GINSBERG H N.Insulin resistance and cardiovascular disease[J].J Clin Invest,2000,106(4):453-458.
[16]SHARMA A,CHETTY V.Obesity,hypertension and insulin resistance[J].Acta Diabet,2005,42(1):S3-8.
[17]胡宾,周玉杰.代谢综合征发病机制的研究进展[J].中华老年心脑血管病杂志,2012,14(3):328-329.
[2] LEGATO M J.Dyslipidemia,gender,and the role of highdensity lipoprotein cholesterol:implications for therapy[J].Am J Cardiol,2000,86(12):15-18.
[3] KEARNEY P M,WHELTON M K,REYNOLDS K,et al.Global burden of hypertension:analysis of worldwide data[J].Lancet,2005,365(9455):217-223.
[4]孙静,黄玉艳,吴雷,等.糖尿病人群高血压的发病率及影响因素[J].中华高血压杂志,2013,21(7):654-658.
[5]曾光霞.中国人口老龄化新特点及影响[J].重庆大学学报(社会科学版),2014,20(2):136-139.
[6]王海涛,张永红,胡一河.我国成人体质量指数及相关指标与肥胖关系的研究进展[J].上海预防医学杂志,2007,19(12):622-623.
[7]中国高血压防治指南修订委员会.中国高血压防治指南2010[J].中华高血压杂志,2011,19(8):701-743.
[8]中国成人血脂异常防治指南制订联合委员会.中国成人血脂异常防治指南[J].中华心血管病杂志,2007,35(5):390-409.
[9]1999World Health Organization.International Society of Hypertension guidelines for the management of hypertension[J].Blood Pressure Supp1,1999(8):9-43.
[10]OSTCHEGA Y,DILLON C F,HUGHES J P,et al.Trends in hypertension prevalence,awareness,treatment,and control in older US adults:data from the National Health and Nutrition Examination Survey 1988to 2004[J].J Am Geri Society,2007,55(7):1056-1065.
[11]王继光.老年高血压现状与问题[J].中国循环杂志,2017,22(11):1049-1051.
[12]谢张伟,方柯,邹伟,等.某高校教职工高血压现状调查[J].保健医学研究与实践,2012,9(3):14-15.
[13]熊有爱.404例40岁以上教职工血脂异常情况分析[J].江西教育学院学报,2010,31(3):82-83.
[14]PINTO E.Blood pressure and ageing[J].Post Med J,2007,83(976):109-114.
[15]GINSBERG H N.Insulin resistance and cardiovascular disease[J].J Clin Invest,2000,106(4):453-458.
[16]SHARMA A,CHETTY V.Obesity,hypertension and insulin resistance[J].Acta Diabet,2005,42(1):S3-8.
[17]胡宾,周玉杰.代谢综合征发病机制的研究进展[J].中华老年心脑血管病杂志,2012,14(3):328-329.