冰片变温红外光谱研究
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摘要
在303~393 K温度范围内,采用变温红外技术(包括变温一维红外光谱、变温二阶导数红外光谱和变温四阶导数红外光谱),开展了冰片的热稳定研究。研究发现,冰片主要存在νas CH3、νas CH2、νs CH3、νC=O、δs CH3、δas CH3和ρCH2等7种红外吸收模式。随着测定温度的升高,冰片的主要官能团的红外吸收强度下降,但对应的红外吸收频率和峰型没有变化。本研究显示出变温红外光谱技术在冰片热稳定性分析中的重要作用。
In the temperature range of 303 ~ 393 K, the thermal stability of ice sheet was studied by means of thermo-changing infrared spectroscopy( including variable temperature one-dimensional spectrum, variable temperature second derivative spectrum and variable temperature fourth derivative spectrum). Research show that there are seven types of infrared absorption modes in the ice chips, such as νas CH3、νas CH2、νs CH3、νC=O、δs CH3、δas CH3和 ρCH2. The infrared absorption intensity of the main functional groups decreases with the increase of temperature, but the corresponding infrared absorption frequency and peak type did not change. The results show that variable temperature infrared spectroscopy plays an important role in thermal stability analysis of borneol.
In the temperature range of 303 ~ 393 K, the thermal stability of ice sheet was studied by means of thermo-changing infrared spectroscopy( including variable temperature one-dimensional spectrum, variable temperature second derivative spectrum and variable temperature fourth derivative spectrum). Research show that there are seven types of infrared absorption modes in the ice chips, such as νas CH3、νas CH2、νs CH3、νC=O、δs CH3、δas CH3和 ρCH2. The infrared absorption intensity of the main functional groups decreases with the increase of temperature, but the corresponding infrared absorption frequency and peak type did not change. The results show that variable temperature infrared spectroscopy plays an important role in thermal stability analysis of borneol.
引文
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[7]于宏伟,赵婷婷,侯腾硕,等.红外光谱技术对尼龙-66结构及性能的研究[J].中国纤检,2018(1):89-92.
[8]黄萍,廖祎婷,姜晓飞,等.天然冰片在不同年龄和性别小鼠体内的含量及樟脑转化量的比较研究[J].时珍国医国药,2011,22(4):810-812.
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[14]冯计民.红外光谱法在微量物证分析中的应用(第1版)[M].北京:化学工业出版社,2010:65-68.
[2]季帅,张军平,吕仕超,等.基于心脑同治学说探讨冰片的临床运用[J].中医杂志,2013,54(2):114-116.
[3]回瑞华,侯冬岩,李铁纯,等.冠心苏合丸中挥发性组分的分析及主成分冰片的测定[J].分析测试学报,2004(5):114-117.
[4]孟华,黄熙,郭军,等.冠心病患者含速效救心丸后体内冰片药动学变化[J].中成药,2003(5):379-382.
[5]谷筱玉,汪嚥,徐可欣,等.冰片的近红外光谱法检测[J].光谱学与光谱分析,2004,24(2):155-157.
[6]周向东,陈迎春,蒲泽佳,等.锦纶用耐久性阻燃剂的合成与应用[J].成都纺织高等专科学校学报,2016,33(1):37-41.
[7]于宏伟,赵婷婷,侯腾硕,等.红外光谱技术对尼龙-66结构及性能的研究[J].中国纤检,2018(1):89-92.
[8]黄萍,廖祎婷,姜晓飞,等.天然冰片在不同年龄和性别小鼠体内的含量及樟脑转化量的比较研究[J].时珍国医国药,2011,22(4):810-812.
[9]L.J.贝拉米.复杂分子的红外光谱(第1版)[M].北京:科学出版社,1975:20-23.
[10]中本一雄.无机和配位化合物的红外和拉曼光谱(第1版)[M].北京:化学工业出版社,1986:227-230.
[11]翁诗甫.傅里叶变换红外光谱分析(第2版)[M].北京:化学工业出版社,2010:357-360.
[12]谢晶曦.红外光谱在有机化学和药物化学中的应用(第2版)[M].北京:科学出版社,1987:360-365.
[13]L.J.贝拉米.复杂分子的红外光谱(第1版)[M].北京:科学出版社,1975:418-420.
[14]冯计民.红外光谱法在微量物证分析中的应用(第1版)[M].北京:化学工业出版社,2010:65-68.