痛经方治疗原发性痛经临床观察
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摘要
目的观察痛经Ⅰ号方和痛经Ⅰ号方治疗原发性痛经的临床疗效。方法选择痛经气滞血瘀型患者90例,分为痛经Ⅰ号方组、膈下逐瘀汤组和西药组;痛经寒凝血瘀型90例,分为痛经Ⅰ号方组、少腹逐瘀汤组和西药组。西药组均服用散利痛片。结果痛经Ⅰ号方组、痛经Ⅰ号方组和西药组的总有效率、疼痛积分、疼痛持续时间积分均优于膈下逐瘀汤组和少腹逐瘀汤组(P <0.05);治疗结束后随访3个月,痛经Ⅰ号方组、痛经Ⅰ号方组总有效率优于膈下逐瘀汤组、少腹逐瘀汤组和西药组,差异具有统计学意义(P <0.05)。结论在治疗痛经的近期疗效中,痛经Ⅰ号方、痛经Ⅰ号方和散利痛均优于膈下逐瘀汤、少腹逐瘀汤;在远期疗效中,痛经Ⅰ号方、痛经Ⅰ号方均优于散利痛和膈下逐瘀汤、少腹逐瘀汤。
Objective To observe the clinical effect of Tongjing decoction for primary dysmenorrhea. Methods A total of 90 cases of primary dysmenorrhea due to qi stagnation and blood stasis were allocated into Tongjing decoction I group, Gexia Zhuyu decoction group, and western medicine group. A total of 90 cases of primary dysmenorrhea due to cold coagulation and blood stasis were allocated into Tongjing decoction II group, Shaofu Zhuyu decoction group, and western medication group. Western medication groups both accepted oral compound paracetamol tablets treatment. Results The total effective rate, pain score and pain duration of Tongjing decoction I group, Tongjing decoction II group and westren medication group were all better than Gexia Zhuyu decoction group and Shaogu Zhuyu decoction group(P<0.05). In the 3 months follow-up visit after treatment, the total effective rate of Tongjing decoction I group, Tongjing decoction II group were both better than Gexia Zhuyu decoction group, Shaogu Zhuyu decoction group and westren medication group(P <0.05), the difference was statistically significant(P <0.05).Conclusion In the short-term efficacy of treating primary dysmenorrhea, Tongjing decoction I, Tongjing decoction II and compound paracetamol tablets have superiority over Gexia Zhuyu decoction group and Shaogu Zhuyu decoction.For the long-term efficacy treating primary dysmenorrhea, Tongjing decoction I and Tongjing decoction II have superiority over Gexia Zhuyu decoction group and Shaogu Zhuyu decoction and compound paracetamol tablets.
Objective To observe the clinical effect of Tongjing decoction for primary dysmenorrhea. Methods A total of 90 cases of primary dysmenorrhea due to qi stagnation and blood stasis were allocated into Tongjing decoction I group, Gexia Zhuyu decoction group, and western medicine group. A total of 90 cases of primary dysmenorrhea due to cold coagulation and blood stasis were allocated into Tongjing decoction II group, Shaofu Zhuyu decoction group, and western medication group. Western medication groups both accepted oral compound paracetamol tablets treatment. Results The total effective rate, pain score and pain duration of Tongjing decoction I group, Tongjing decoction II group and westren medication group were all better than Gexia Zhuyu decoction group and Shaogu Zhuyu decoction group(P<0.05). In the 3 months follow-up visit after treatment, the total effective rate of Tongjing decoction I group, Tongjing decoction II group were both better than Gexia Zhuyu decoction group, Shaogu Zhuyu decoction group and westren medication group(P <0.05), the difference was statistically significant(P <0.05).Conclusion In the short-term efficacy of treating primary dysmenorrhea, Tongjing decoction I, Tongjing decoction II and compound paracetamol tablets have superiority over Gexia Zhuyu decoction group and Shaogu Zhuyu decoction.For the long-term efficacy treating primary dysmenorrhea, Tongjing decoction I and Tongjing decoction II have superiority over Gexia Zhuyu decoction group and Shaogu Zhuyu decoction and compound paracetamol tablets.
引文
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[12]郑仁省.芍药甘草汤对痛经患者血清IL-1β、TNF-α及疼痛的影响[J].长春中医药大学学报,2017,33(4):614-616.
[13]刘蕊.温和灸不同时间因素对寒湿凝滞型原发性痛经止痛效应的临床研究[J].吉林中医药,2017,37(10):1056-1058.
[2]王娟.痛经的中医病机及治疗时机把握[J].吉林中医药,2012,32(1):45-47.
[3]马宝璋.中医妇科学[M].上海:上海科学技术出版社,2001:79.
[4]朱美文,倪建俐.痛经中医证候的德菲尔法专家咨询研究[J].世界中西医结合杂志,2018,13(10):1399-1402.
[5]上海市卫生局,中华医学会上海分会.妇产科诊疗常规[M].上海:上海科学技术出版社,1999:61-62.
[6]国家中医药管理局医政司.中医病症诊断疗效标准[M].北京:中国中医药出版社,2014:234.
[7]中华人民卫生部药政管理局.中药新药临床研究指导原则[M].北京:中国医药科技出版社,1993:263-265.
[8]柳孝先,张梓乐,李晨.实用社区医师手册[M].北京:人民军医出版社,2003:424-426.
[9]倪建俐.单味中药治疗原发性痛经规律探讨[J].吉林中医药,2018,38(5):584-587.
[10]蒋丹丹.针灸联合少腹逐瘀汤治疗原发性痛经的临床观察[J].北方药学,2017,14(3):74-76.
[11]汪杏.前列腺素在月经性偏头痛发病机制中的作用[J]吉林中医药,2017,37(6):586-588.
[12]郑仁省.芍药甘草汤对痛经患者血清IL-1β、TNF-α及疼痛的影响[J].长春中医药大学学报,2017,33(4):614-616.
[13]刘蕊.温和灸不同时间因素对寒湿凝滞型原发性痛经止痛效应的临床研究[J].吉林中医药,2017,37(10):1056-1058.