石墨烯基环糊精传感器的构建及对组氨酸对映体的电位识别
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摘要
以具备手性识别作用的环糊精聚合物为手性选择剂,以石墨烯为手性放大材料,通过层层修饰的方法构建了石墨烯基环糊精聚合膜电位识别传感器.由所构建的传感器测得的组氨酸对映体的氧化峰电位存在明显的差异,电位差值近100 m V,且不同比例的组氨酸对映体混合溶液的氧化峰电位值与对映体过量值呈现良好的线性关系.据此,建立了一种通过电位同时识别组氨酸对映体两组分的新方法.
Cyclodextrin polymer with chiral recognition function were selected as chiral selectors,and graphene materials with excellent performance were used to further amplify the difference in peak potential response,cyclodextrin polymeric membrane sensor based on graphene was constructed by layer modification.There was a significant difference in the peak potential response between two components of histidine enantiomer. The potential difference is nearly 100 m V. A good linear relationship was showed between the oxidation peak potential and enantiomeric excess of the mixed solution. The mixed solution consists of different ratios of two components histidine enantiomer. A new method for simultaneously identifying two components of histidine enantiomer by potential response can be established.
Cyclodextrin polymer with chiral recognition function were selected as chiral selectors,and graphene materials with excellent performance were used to further amplify the difference in peak potential response,cyclodextrin polymeric membrane sensor based on graphene was constructed by layer modification.There was a significant difference in the peak potential response between two components of histidine enantiomer. The potential difference is nearly 100 m V. A good linear relationship was showed between the oxidation peak potential and enantiomeric excess of the mixed solution. The mixed solution consists of different ratios of two components histidine enantiomer. A new method for simultaneously identifying two components of histidine enantiomer by potential response can be established.
引文
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[5] Kang Y.,Oh J.,Kim Y.,Kim J. S.,Kim H.,Chem. Commun.,2010,46(31),5665—5667
[6] Han C.,Hou X.,Zhang H.,Guo W.,Li. H.,Jiang L.,J. Am. Chem. Soc.,2011,133(20),7644—7647
[7] Nie R.,Bo X.,Wang H.,Zeng L.,Guo L.,Electrochem. Commun.,2013,27,112—115
[8] Geim A. K.,Katsnelson M. I.,Novoselov K. S.,Nat. Phys.,2006,2(9),620—625
[9] Chang J.,Chang K.,Hu C.,Cheng W.,Zen J.,Electrochem. Commun.,2010,12(4),596—599
[10] Kauppila J.,Kunnas P.,Damlin P.,Electrochimi. Acta,2013,89,84—89
[11] Zhang D.,Fang Y.,Miao Z.,Ma M.,Du X.,Electrochimi. Acta,2013,107,656—663
[12] Corona-Avenda1o S.,Ramírez-Silva M. T.,Romero-Romo M.,Electrochim. Acta,2013,89,854—860
[13] Roa Morales G.,Ramírez Silva T.,Galicia L.,J. Solid State Electrochem.,2003,7(6),355—360
[14] Liu Y. R.,Wei M.T.,Hu Y.,Zhu L. L.,Du J. Y.,Sens. Actuators B:Chem.,2018,255,544—551
[15] Wang L.,Int. J. Electrochem. Sc.,2018,13,1594—1602
[16] Cheol-Joo Kim. A.,Sánchez C.,Zack Z.,Yui O.,Nat. Nanotechnol.,2016,11(6),520—525
[17] Trojanowicz M.,Electrochem. Commun.,2014,38,47—52
[18] Liu Y. L.,Zhu L. L.,Hu Y.,Peng X. S.,Du J.,Food. Chem.,2017,221,1128—1134
[19] Corona-Avenda1o S.,Ramírez-Silva M. T.,Romero-Romo M.,Rojas-Hernández A.,Palomar-PardavéM.,Electrochim. Acta,2013,89,854—860
[20] Zhao Y.,Huang Y.,Zhu H.,Zhu Q.,Xia Y.,J. Am. Chem. Soc.,2016,138(51),16645—16654
[21] Fraschini C.,Vignon M. R.,Carbohyd. Res.,2000,328(4),585—589
[22] Liu Y. R.,Zhu L. L.,Hu Y.,Peng X. S.,Du J. Y.,Food. Chem.,2017,221,1128—1134
[23] Ates S.,Zor E.,Akin I.,Bingol H.,Alpaydin S.,Akgemci E. G.,Anal. Chim. Acta,2017,970,30—37
[24] Jung I.,Pelton M.,Piner R.,Dikin D. A.,Stankovich S.,Watcharotone S.,Hausner M.,Ruoff R. S.,Nano. Lett.,2007,7(12),3569—3575
[25] Ding S.,Cao S.,Zhu A.,Shi G.,Anal. Chem.,2016,88(24),12219—12226
[26] Tian F.,Mou S. F.,J. North Univ. China(Natural Science Edition),2010,31(5),499—503(田芳,牟善峰.中北大学学报(自然科学版),2010,31(5),499—503)
[27] Liao H.,Zhang Z.,Nie L.,Yao S.,J. Biochem. Bioph. Meth.,2004,59(1),75—87
[28] Liu C.,Li B.,Xu C.,Microchim. Acta,2014,181(11/12),1407—1413