2010～2014年浙江省肿瘤登记地区脑肿瘤发病与死亡分析
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摘要
[目的]评估2010～2014年浙江省肿瘤登记地区脑肿瘤的发病与死亡情况。[方法]数据来源于浙江省14个肿瘤登记处的脑肿瘤发病、死亡及人口资料。分别计算发病(死亡)例数、粗发病率(死亡率)、构成比和顺位、中国标准人口构成(中标率)、Segi’s世界标准人口构成(世标率)、累积率、截缩率、年龄别发病率(死亡率)等指标。[结果 ] 2010～2014年浙江省14个肿瘤登记地区共计报告脑肿瘤新发病例5011例,占癌症新发病例的2.54%。脑肿瘤发病率为8.55/10万,中标率为6.05/10万,世标率为5.96/10万,居癌症发病顺位的第12位。女性中标率是男性的1.10倍,城市地区中标率是农村的1.02倍。脑肿瘤年龄别发病率随年龄增长而增加,在75～岁组达到高峰(26.32/10万)。脑肿瘤发病率历年变化呈波动增长趋势,发病率从2010年的8.57/10万上升至2014年的9.07/10万,增幅为5.83%。共计报告脑肿瘤死亡病例2577例,占癌症死亡病例的2.37%。脑肿瘤死亡率为4.40/10万,中标率为2.95/10万,世标率为2.94/10万,居癌症死亡顺位的第8位。男性中标率是女性的1.30倍,农村地区中标率是城市的1.02倍。脑肿瘤年龄别死亡率在0～39岁期间处于较低水平,在80～岁组达到高峰(20.41/10万)。脑肿瘤死亡率历年变化呈总体增长趋势,死亡率从2010年的4.28/10万上升至2014年的4.81/10万,增幅为12.38%。[结论]浙江省肿瘤登记地区脑肿瘤死亡呈上升趋势,发病率处于较高水平,特别是女性。应加强脑肿瘤的预防和控制工作。
[Purpose] To estimate the incidence and mortality of brain tumor in Zhejiang cancer registration areas from 2010 to 2014. [Methods] Data from 14 cancer registration areas of Zhejiang Province were collected. Number of cases,crude rates,proportions,age-standardized rates,cumulate rates,truncated rates and age-specific rates were calculated. [Results] There were 5011 newly diagnosed brain tumor cases in Zhejiang cancer registration areas,accounting for 2.54% of all the new cancer cases. The incidence rate of brain tumor was 8.55/10~5,and the age-standardized incidence rate by Chinese population(ASR China) was 6.05/10~5,ranking the 12 th in cancer incidence spectrum of anatomic sites. The ASR China in female was 1.10 times as high as that in males. The ASR China in urban areas was 1.02 times as high as that in rural areas. Age-specific incidence of brain tumor increased along with ages,and peaked in age group of 75～ years(26.32/10~5). The annual incidence rate of brain tumor increased from 8.57/10~5 in 2010 to 9.07/10~5 in 2014,with an increase of 5.83%. A total of 2577 deaths caused by brain tumor were reported from2010～2014,accounting for 2.37% of all the cancer death cases. Mortality rate of brain tumor was 4.40/10~5,with the ASR China of 2.95/10~5,ranking the 8 th in cancer mortality spectrum of anatomic sites. The ASR China in males was 1.30 times as high as that in females. The ASR China in rural areas was 1.02 times as high as that in urban areas. Age-specific mortality of brain tumor remained low among 0～39 years old,and peaked at age group of 80～ years(20.41/10~5). The annual mortality rate of brain tumor increased from 4.28/10~5 in 2010 to 4.81/10~5 in 2014,with an increase of 12.38%. [Conclusion] The mortality of brain tumor in Zhejiang cancer registration areas increases,and the incidence rate is at a relatively high level,especially for females. The prevention and control for brain,nervous system cancer must be strengthened.
[Purpose] To estimate the incidence and mortality of brain tumor in Zhejiang cancer registration areas from 2010 to 2014. [Methods] Data from 14 cancer registration areas of Zhejiang Province were collected. Number of cases,crude rates,proportions,age-standardized rates,cumulate rates,truncated rates and age-specific rates were calculated. [Results] There were 5011 newly diagnosed brain tumor cases in Zhejiang cancer registration areas,accounting for 2.54% of all the new cancer cases. The incidence rate of brain tumor was 8.55/10~5,and the age-standardized incidence rate by Chinese population(ASR China) was 6.05/10~5,ranking the 12 th in cancer incidence spectrum of anatomic sites. The ASR China in female was 1.10 times as high as that in males. The ASR China in urban areas was 1.02 times as high as that in rural areas. Age-specific incidence of brain tumor increased along with ages,and peaked in age group of 75～ years(26.32/10~5). The annual incidence rate of brain tumor increased from 8.57/10~5 in 2010 to 9.07/10~5 in 2014,with an increase of 5.83%. A total of 2577 deaths caused by brain tumor were reported from2010～2014,accounting for 2.37% of all the cancer death cases. Mortality rate of brain tumor was 4.40/10~5,with the ASR China of 2.95/10~5,ranking the 8 th in cancer mortality spectrum of anatomic sites. The ASR China in males was 1.30 times as high as that in females. The ASR China in rural areas was 1.02 times as high as that in urban areas. Age-specific mortality of brain tumor remained low among 0～39 years old,and peaked at age group of 80～ years(20.41/10~5). The annual mortality rate of brain tumor increased from 4.28/10~5 in 2010 to 4.81/10~5 in 2014,with an increase of 12.38%. [Conclusion] The mortality of brain tumor in Zhejiang cancer registration areas increases,and the incidence rate is at a relatively high level,especially for females. The prevention and control for brain,nervous system cancer must be strengthened.
引文
[1]Duan JJ,Chen WQ,Yang NN,et al.An analysis on incidence and mortality of brain tumor from 2003 to 2007 in China[J].China Cancer,2012,21(9):644-649.[段纪俊,陈万青,杨念念,等.2003-2007年中国脑瘤死亡与死亡分析[J].中国肿瘤,2012,21(9):644-649.]
[2]Li HZ,Mao WM,Wang XH,et al.Incidence and mortality of brain tumor in areas with cancer registration of Zhejiang Province,from 2000 to 2009[J].Chinese Journal of Epidemiology,2014,35(3):285-288.[李辉章,毛伟敏,汪祥辉,等.浙江省2000-2009年肿瘤登记地区脑肿瘤发病与死亡分析[J].中华流行病学杂志,2014,35(3):285-288.]
[3]National Cancer Center.Chinese guideline for cancer registration 2016[M].Beijing:People’s Medical Publishing House,2016.59-75.[国家癌症中心.中国肿瘤登记工作指导手册2016[M].北京:人民卫生出版社,2016.59-75.]
[4]Parkin DM,Chen VW,Ferlay J.et al.Comparability and quality control in cancer registration.IACR technical report No.19[M].Lyon:International Agency for Research on Cancer,1994.
[5]He J,Chen WQ.Chinese cancer registry annual report 2014[M].Beijing:Tsinghua University Press,2017.[赫捷,陈万青.2014年中国肿瘤登记年报[M].北京:清华大学出版社,2017.]
[6]Xia SC.Technical report on disease prevention and control in Zhejiang Province in 2015[M].Hangzhou:Zhejiang Science and Technology Press,2016.156-160.[夏时畅.2015年浙江省疾病预防控制技术报告[M].杭州:浙江科学技术出版社,2016.156-160.]
[7]Du LB,Yu CD,Li HZ,et al.Strengthening the system construction,constructing Zhejiang provincial cancer prevention and control network[J].China Cancer,2017,26(10):749-750.[杜灵彬,余传定,李辉章,等.加强体系建设,构建浙江省肿瘤防治网络[J].中国肿瘤,2017,26(10):749-750.]
[8]Wang WB.Clinical analysis of chemotherapy combined with three-dimensional conformal radiotherapy for brain tumors[J].Chinese Journal of Practical Nervous Diseases,2016,19(5):68-70.[王文彬.化疗联合三维适形放射治疗脑瘤临床分析[J].中国实用神经疾病杂志,2016,19(5):68-70.]
[9]Liu Y.Clinical study and therapeutic observation of huatan,zhuyu and xiaoliu decoction in the treatment of primary cerebral tumor[M].Qinhuangdao:XianDaiYangSheng,2016.39.[刘艳.化痰逐瘀消瘤汤治疗原发性脑瘤临床研究及疗效观察[M].秦皇岛:现代养生,2016.39.]
[2]Li HZ,Mao WM,Wang XH,et al.Incidence and mortality of brain tumor in areas with cancer registration of Zhejiang Province,from 2000 to 2009[J].Chinese Journal of Epidemiology,2014,35(3):285-288.[李辉章,毛伟敏,汪祥辉,等.浙江省2000-2009年肿瘤登记地区脑肿瘤发病与死亡分析[J].中华流行病学杂志,2014,35(3):285-288.]
[3]National Cancer Center.Chinese guideline for cancer registration 2016[M].Beijing:People’s Medical Publishing House,2016.59-75.[国家癌症中心.中国肿瘤登记工作指导手册2016[M].北京:人民卫生出版社,2016.59-75.]
[4]Parkin DM,Chen VW,Ferlay J.et al.Comparability and quality control in cancer registration.IACR technical report No.19[M].Lyon:International Agency for Research on Cancer,1994.
[5]He J,Chen WQ.Chinese cancer registry annual report 2014[M].Beijing:Tsinghua University Press,2017.[赫捷,陈万青.2014年中国肿瘤登记年报[M].北京:清华大学出版社,2017.]
[6]Xia SC.Technical report on disease prevention and control in Zhejiang Province in 2015[M].Hangzhou:Zhejiang Science and Technology Press,2016.156-160.[夏时畅.2015年浙江省疾病预防控制技术报告[M].杭州:浙江科学技术出版社,2016.156-160.]
[7]Du LB,Yu CD,Li HZ,et al.Strengthening the system construction,constructing Zhejiang provincial cancer prevention and control network[J].China Cancer,2017,26(10):749-750.[杜灵彬,余传定,李辉章,等.加强体系建设,构建浙江省肿瘤防治网络[J].中国肿瘤,2017,26(10):749-750.]
[8]Wang WB.Clinical analysis of chemotherapy combined with three-dimensional conformal radiotherapy for brain tumors[J].Chinese Journal of Practical Nervous Diseases,2016,19(5):68-70.[王文彬.化疗联合三维适形放射治疗脑瘤临床分析[J].中国实用神经疾病杂志,2016,19(5):68-70.]
[9]Liu Y.Clinical study and therapeutic observation of huatan,zhuyu and xiaoliu decoction in the treatment of primary cerebral tumor[M].Qinhuangdao:XianDaiYangSheng,2016.39.[刘艳.化痰逐瘀消瘤汤治疗原发性脑瘤临床研究及疗效观察[M].秦皇岛:现代养生,2016.39.]