急性心肌梗死后再发脑梗死的危险因素分析
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摘要
目的分析急性心肌梗死(AMI)再发脑梗死的危险因素。方法从2009-02—2016-08许昌市中心医院南区医院AMI病例中选取AMI后6个月内再发脑梗死40例为观察组,另筛选同期收治的280例单纯AMI患者为对照组,对比2组临床资料,筛选单因素分析有差异指标行多因素Logistic回归分析,探讨AMI后再发脑梗死的危险因素。结果年龄、吸烟、心房颤动、高脂血症、高血压、糖尿病、HDL-C、收缩压均为引发AMI后再发脑梗死的独立危险因素(P<0.05),以高脂血症相关性最强。结论在AMI治疗过程中应严密关注高龄、长期吸烟、心房颤动、高脂血症、高血压、糖尿病、HDL-C异常、收缩压异常患者病情变化,做到早预防、早治疗,最大限度降低AMI患者再发脑梗死风险。
Objective To analyze the risk factors of recurrent cerebral infarction after acute myocardial infarction(AMI).Methods 40 patients with recurrent cerebral infarction within 6 months after AMI were selected from patients with AMI who were admitted to the hospital from February 2009 to August 2016 and they were included in the observation group.Another 280 patients with simple AMI were selected as the control group.The general clinical data and pathological data were compared between the two groups.Indexes with differences afterunivariate analysis were analyzed by Logistic regression analysis to identify the risk factors of recurrent cerebral infarction after AMI.Results Age,smoking,atrial fibrillation,hyperlipidemia,hypertension,diabetes,HDL-C and systolic blood pressure were independent risk factors for recurrent cerebral infarction after AMI(P<0.05),and the correlation with hyperlipidemia was the strongest.Conclusion Close attention should be paid to the elderly,long-term smoking patients,patients with atrial fibrillation,hyperlipidemia,hypertension,diabetes,abnormal HDL-C or systolic blood pressure disorders in the clinical treatment of AMI.Strengthening the control of the disease in such patients,early prevention and treatment,can minimize the risk of recurrent cerebral infarction in patients with AMI.
Objective To analyze the risk factors of recurrent cerebral infarction after acute myocardial infarction(AMI).Methods 40 patients with recurrent cerebral infarction within 6 months after AMI were selected from patients with AMI who were admitted to the hospital from February 2009 to August 2016 and they were included in the observation group.Another 280 patients with simple AMI were selected as the control group.The general clinical data and pathological data were compared between the two groups.Indexes with differences afterunivariate analysis were analyzed by Logistic regression analysis to identify the risk factors of recurrent cerebral infarction after AMI.Results Age,smoking,atrial fibrillation,hyperlipidemia,hypertension,diabetes,HDL-C and systolic blood pressure were independent risk factors for recurrent cerebral infarction after AMI(P<0.05),and the correlation with hyperlipidemia was the strongest.Conclusion Close attention should be paid to the elderly,long-term smoking patients,patients with atrial fibrillation,hyperlipidemia,hypertension,diabetes,abnormal HDL-C or systolic blood pressure disorders in the clinical treatment of AMI.Strengthening the control of the disease in such patients,early prevention and treatment,can minimize the risk of recurrent cerebral infarction in patients with AMI.
引文
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[10] 杨贤,郑萍.临床药师参与1例亚急性心肌梗死合并腔隙性脑梗及深静脉血栓患者的抗栓治疗体会[J].药学实践杂志,2017,35(2):161-164.
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[12] MALHOTRA K,CHANG J J,KHUNGER A,et al.Minocycline for acute stroke treatment:a systematic review and meta-analysis of randomized clinical trials[J].J Neurol,2018,265(8):1871-1879.DOI:10.1007/s00415-018-8935-3.
[13] KIM J,BUSHNELL C D,LEE H S,et al.Effect of Adherence to Antihypertensive Medication on the Long-Term Outcome After Hemorrhagic Stroke in Korea[J].Hypertension,2018,72(2):391-398.DOI:10.1161/HYPERTENSIONAHA.118.11139.
[14] 刘仁光,陈阳.心肌梗死与心电图诊断新标准[J].临床心电学杂志,2012,21(6):441-442.
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