老年高血压合并高尿酸血症影响因素分析
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摘要
目的探讨老年原发高血压病患者合并高尿酸血症的影响因素。方法选择2017年6月—2018年3月我院体检人员532例,检出高血压患者136例,将高血压并高尿酸血症69例为观察组,未合并高尿酸血症的高血压病患者67例为对照组。分析2组临床资料,并采用Logistic回归分析进行危险因素分析。结果肥胖、糖尿病高胆固醇血症、高甘油三酯血症及饮酒是高血压合并高尿酸血症的危险因素(P <0. 05)。结论老年原发高血压病患者合并高尿酸血症较为普遍,临床应针对危险因素进行有效预防和治疗,提高患者生活质量。
Objective To investigate influencing factors elderly patients with hypertension associated by hyperuricemia. Methods A total of 136 hypertension patients from 532 people taking health examination during June 2017 and March 2018 were enrolled in the study,of which 69 hypertension patients with hyperuricemia were selected as observation group,and other 67 hypertension patients without hyperuricemia were selected as control group. Clinical data was analyzed,and Logistic regression analysis was used to analyze risk factors in two groups. Results Obesity,hypercholesterolemia,hypertriglyceridemia and drinking were risk factors for elderly patients with hypertension associated by hyperuricemia( P < 0. 05). Conclusion Hyperuricemia is a common complication in elderly patients with essential hypertension,and therefore effective prevention and treatment should be carried out according to risk factors in order to improve life quality of patients.
Objective To investigate influencing factors elderly patients with hypertension associated by hyperuricemia. Methods A total of 136 hypertension patients from 532 people taking health examination during June 2017 and March 2018 were enrolled in the study,of which 69 hypertension patients with hyperuricemia were selected as observation group,and other 67 hypertension patients without hyperuricemia were selected as control group. Clinical data was analyzed,and Logistic regression analysis was used to analyze risk factors in two groups. Results Obesity,hypercholesterolemia,hypertriglyceridemia and drinking were risk factors for elderly patients with hypertension associated by hyperuricemia( P < 0. 05). Conclusion Hyperuricemia is a common complication in elderly patients with essential hypertension,and therefore effective prevention and treatment should be carried out according to risk factors in order to improve life quality of patients.
引文
[1]陈可珍.高尿酸血症合并高血压临床特点及预防分析[J].中国卫生产业,2014,11(10):103,105.
[2]李轶.高血压合并2型糖尿病患者血尿酸及血清同型半胱氨酸联合检测的临床意义分析[J].中西医结合心血管病杂志:电子版,2015,3(35):119,122.
[3] Bonakdaran S,Hami M,Shakeri M T. Hyperuricemia and albuminuria in patients with type 2 diabetes mellitus[J].Iran J Kidney Dis,2011,5(1):21-24.
[4]李钰,李姣,陈红.脂肪肝与糖尿病高血压及体质量指数的相关性分析[J].现代中西医结合杂志,2015,24(15):1640-1641,1646.
[5] Lastra G,Syed S,Kurukulasuriya L R,etc. Type 2 diabetes mellitus and hypertension:an update[J]. Endocrinol Metab Clin North Am,2014,43(1):103-122.
[6] Viazzi F,Bonino B,Ratto E,et al. Hyperuricemia,diabetes and hypertension[J]. G Ital Nefrol,2015,32 Suppl 62:gin/32. S62. 10.
[7] Wang S F,Shu L,Wang S,et al. Gender difference in the association of hyperuricemia with hypertension in a middle-aged Chinese population[J]. Blood Press,2014,23(6):339-344.
[8]吴蕾,何耀,刘淼,等.北京某社区不同性别老年人群血尿酸水平与高血压的现况研究[J].中华疾病控制杂志,2017,21(3):223-227.
[9] Wu L,He Y,Jiang B,et al. Association between serum uric acid level and hypertension in a Chinese elderly rural population[J]. Clin Exp Hypertens,2017,39(6):505-512.
[10]金楠,李革,李会,等.中国大陆地区成年人高血压前期发生率及危险因素的meta分析[J].南方医科大学学报,2013,33(12):1738-1743.
[11] Paula T P,Viana LV,Neto A T,et al. Effects of the DASH Diet and Walking on Blood Pressure in Patients With Type 2 Diabetes and Uncontrolled Hypertension:A Randomized Controlled Trial[J]. Clin Hypertens(Greenwich),2015,17(11):895-901.
[12] Jacobs J M,Stessman J,Ein-Mor E,et al. Hypertension and 5-year mortality among 85-year-olds:the Jerusalem Longitudinal Study[J]. J Am Med Dir Assoc,2012,13(759):e1-6.
[13]胡烨文,王世奇,陈晓敏,等.原发性高血压老年患者高尿酸血症的影响因素研究[J].浙江医学,2017,39(7):549-550,554.
[14]高景然,林可意,娜佳. 2型糖尿病合并高尿酸血症对高血压患病风险的影响分析[J].中国医药科学,2018,8(3):89-92.
[15]黄雨晴,丁森华,冯颖青,等.高龄老年高血压患者高尿酸血症相关因素分析[J].中华临床医师杂志:电子版,2016,10(17):2531-2534.
[16]邢慧媛,刘琰,赵艾,等.吸烟、饮酒和膳食因素对高尿酸血症人群中高血压的影响[J].中华疾病控制杂志,2018,22(6):555-559.
[17]邓丽群,左慧娟,王锦改,等.我国不同地区高血压患者疾病管理现状及效果分析[J].中国医药,2018,13(2):1791-1796.
[18]国华,丁存涛,孙希鹏,等.老年高血压患者血清尿酸水平与代谢综合征的相关性研究[J].中华老年心脑血管病杂志,2018,20(11):1124-1128.
[19]孙超,李南方,周玲.高尿酸血症与心血管疾病的研究进展[J].中国综合临床,2014,30(12):1340-1343.
[20]杨婕.老年人高尿酸血症与高血压病相关性分析[J].中华保健医学杂志,2014,16(3):182-183.
[21]朱巧红,毕光宇.非布司他治疗慢性肾衰竭合并高尿酸血症的临床观察[J].中国煤炭工业医学杂志,2015,18(12):2042-2044.
[2]李轶.高血压合并2型糖尿病患者血尿酸及血清同型半胱氨酸联合检测的临床意义分析[J].中西医结合心血管病杂志:电子版,2015,3(35):119,122.
[3] Bonakdaran S,Hami M,Shakeri M T. Hyperuricemia and albuminuria in patients with type 2 diabetes mellitus[J].Iran J Kidney Dis,2011,5(1):21-24.
[4]李钰,李姣,陈红.脂肪肝与糖尿病高血压及体质量指数的相关性分析[J].现代中西医结合杂志,2015,24(15):1640-1641,1646.
[5] Lastra G,Syed S,Kurukulasuriya L R,etc. Type 2 diabetes mellitus and hypertension:an update[J]. Endocrinol Metab Clin North Am,2014,43(1):103-122.
[6] Viazzi F,Bonino B,Ratto E,et al. Hyperuricemia,diabetes and hypertension[J]. G Ital Nefrol,2015,32 Suppl 62:gin/32. S62. 10.
[7] Wang S F,Shu L,Wang S,et al. Gender difference in the association of hyperuricemia with hypertension in a middle-aged Chinese population[J]. Blood Press,2014,23(6):339-344.
[8]吴蕾,何耀,刘淼,等.北京某社区不同性别老年人群血尿酸水平与高血压的现况研究[J].中华疾病控制杂志,2017,21(3):223-227.
[9] Wu L,He Y,Jiang B,et al. Association between serum uric acid level and hypertension in a Chinese elderly rural population[J]. Clin Exp Hypertens,2017,39(6):505-512.
[10]金楠,李革,李会,等.中国大陆地区成年人高血压前期发生率及危险因素的meta分析[J].南方医科大学学报,2013,33(12):1738-1743.
[11] Paula T P,Viana LV,Neto A T,et al. Effects of the DASH Diet and Walking on Blood Pressure in Patients With Type 2 Diabetes and Uncontrolled Hypertension:A Randomized Controlled Trial[J]. Clin Hypertens(Greenwich),2015,17(11):895-901.
[12] Jacobs J M,Stessman J,Ein-Mor E,et al. Hypertension and 5-year mortality among 85-year-olds:the Jerusalem Longitudinal Study[J]. J Am Med Dir Assoc,2012,13(759):e1-6.
[13]胡烨文,王世奇,陈晓敏,等.原发性高血压老年患者高尿酸血症的影响因素研究[J].浙江医学,2017,39(7):549-550,554.
[14]高景然,林可意,娜佳. 2型糖尿病合并高尿酸血症对高血压患病风险的影响分析[J].中国医药科学,2018,8(3):89-92.
[15]黄雨晴,丁森华,冯颖青,等.高龄老年高血压患者高尿酸血症相关因素分析[J].中华临床医师杂志:电子版,2016,10(17):2531-2534.
[16]邢慧媛,刘琰,赵艾,等.吸烟、饮酒和膳食因素对高尿酸血症人群中高血压的影响[J].中华疾病控制杂志,2018,22(6):555-559.
[17]邓丽群,左慧娟,王锦改,等.我国不同地区高血压患者疾病管理现状及效果分析[J].中国医药,2018,13(2):1791-1796.
[18]国华,丁存涛,孙希鹏,等.老年高血压患者血清尿酸水平与代谢综合征的相关性研究[J].中华老年心脑血管病杂志,2018,20(11):1124-1128.
[19]孙超,李南方,周玲.高尿酸血症与心血管疾病的研究进展[J].中国综合临床,2014,30(12):1340-1343.
[20]杨婕.老年人高尿酸血症与高血压病相关性分析[J].中华保健医学杂志,2014,16(3):182-183.
[21]朱巧红,毕光宇.非布司他治疗慢性肾衰竭合并高尿酸血症的临床观察[J].中国煤炭工业医学杂志,2015,18(12):2042-2044.